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Thread: MSM cream for rosacea subtype one

  1. #1
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    Default MSM cream for rosacea subtype one

    Hi, I just read a study saying that a topical MSM and silymarin helps rosacea subtype 1.

    Link to study:

    https://www.ncbi.nlm.nih.gov/pubmed/18254805

    Results and Conclusions:
    RESULTS:
    A statistically significant improvement was observed in many clinical and instrumental parameters investigated (P < 0.001). In particular, improvement of skin redness, papules, itching, hydration, and skin color occurred.

    CONCLUSIONS:
    The combination of silymarin and S-MSM can be useful in managing symptoms and condition of rosacea skin, especially in the rosacea subtype 1 erythemato-telangiectatic phase. The action can be considered multicentric and multiphase because of the direct modulating action on cytokines and angiokines normally involved and up-regulated in the case of such skin condition.


    Does anyone use an S-MSM cream ?, it seems that it should help subtype 1 according to the study.

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    Quote Originally Posted by andydoyle View Post
    Hi, I just read a study saying that a topical MSM and silymarin helps rosacea subtype 1.

    Link to study:

    https://www.ncbi.nlm.nih.gov/pubmed/18254805

    Results and Conclusions:
    RESULTS:
    A statistically significant improvement was observed in many clinical and instrumental parameters investigated (P < 0.001). In particular, improvement of skin redness, papules, itching, hydration, and skin color occurred.

    CONCLUSIONS:
    The combination of silymarin and S-MSM can be useful in managing symptoms and condition of rosacea skin, especially in the rosacea subtype 1 erythemato-telangiectatic phase. The action can be considered multicentric and multiphase because of the direct modulating action on cytokines and angiokines normally involved and up-regulated in the case of such skin condition.


    Does anyone use an S-MSM cream ?, it seems that it should help subtype 1 according to the study.
    I've tried the cream but didn't find it very helpful. However, I do find Solgar MSM tablets helpful - I take 3 1000mg per day. The best cream I've found is Zhongzhou cream.

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    Quote Originally Posted by andydoyle View Post
    Hi, I just read a study saying that a topical MSM and silymarin helps rosacea subtype 1.

    Link to study:

    https://www.ncbi.nlm.nih.gov/pubmed/18254805

    Results and Conclusions:
    RESULTS:
    A statistically significant improvement was observed in many clinical and instrumental parameters investigated (P < 0.001). In particular, improvement of skin redness, papules, itching, hydration, and skin color occurred.

    CONCLUSIONS:
    The combination of silymarin and S-MSM can be useful in managing symptoms and condition of rosacea skin, especially in the rosacea subtype 1 erythemato-telangiectatic phase. The action can be considered multicentric and multiphase because of the direct modulating action on cytokines and angiokines normally involved and up-regulated in the case of such skin condition.


    Does anyone use an S-MSM cream ?, it seems that it should help subtype 1 according to the study.

    Seems like it worked well using the cream in the study. Problem is there is no prescription version (or any made to a regulated controlled standard) available. On places like amazon I doubt those versions would work compared to the cream made in the study.
    "Silymarin cream" in other published trials is also meant to work for melasma. I searched melasma forums about the different Silymarin creams being bough on amazon/ebay and the consensus is they don't work, because they are not produced under any standard or regulation. Some had tried to create the cream from published journals but without the exact amounts/methods/ingredients used etc.


    I've attached the full journal article below if you haven't read it.
    Attached Files

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    Here's another article about silymarin cream: https://www.dovepress.com/formulatio...t-article-DDDT

    You can see in the article that silymarin is very difficult to make into a cream because it has very low solubility. A reviewer on amazon said that the food grade supplements smelled like cat urine, so there's another problem for topical use.

    In my opinion the MSM is not the active ingredient -- the silymarin is. I say this because of the article linked above, and because MSM is super easy to formulate with, being soluble in water, but it doesn't seem to make much difference except as a useful, organic preservative.

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    Thanks for all the responses, I got some MSM today (vegavero brand) to supplement with for the benefits to rosacea, skin hair and nails. Its a shame that there isn't a cream that can be made using silymarin and MSM. MSM seems to be one of the most popular anti-inflammatory supplements people with rosacea take, so I was hoping the cream would also be helpful.

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    Quote Originally Posted by andydoyle View Post
    Thanks for all the responses, I got some MSM today (vegavero brand) to supplement with for the benefits to rosacea, skin hair and nails. Its a shame that there isn't a cream that can be made using silymarin and MSM. MSM seems to be one of the most popular anti-inflammatory supplements people with rosacea take, so I was hoping the cream would also be helpful.
    Yeah,i am taking also MSM supplement but other brand name is vitíall+ ,i wonder if itís a good brand, i heard that there is fake brand that sells it as pure msm
    Is it true ?


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    What brand did you hear is the fake brand, vit'all+ or vegavero ?

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    Quote Originally Posted by asm View Post
    Yeah,i am taking also MSM supplement but other brand name is vitíall+ ,i wonder if itís a good brand, i heard that there is fake brand that sells it as pure msm
    Is it true ?


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    I've tried other brands, but didn't find them very helpful, so I've stuck with Solgar for about ten years now. I find it helps with both the flushing and pustules/papules. As with all supplements, it is not a solution used by alone, but needs to be used alongside dietary changes and medications if necessary.

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    Quote Originally Posted by andydoyle View Post
    What brand did you hear is the fake brand, vit'all+ or vegavero ?
    None of them i just watched a recent video of dr berg talking about the importance of taking msm and i go through the comments and people there are saying that most of the companies are not selling pure msm they mix it with petroleum that is why i come back to the group to find if anyone here is having any idea


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    Quote Originally Posted by antwantsclear View Post
    I've tried other brands, but didn't find them very helpful, so I've stuck with Solgar for about ten years now. I find it helps with both the flushing and pustules/papules. As with all supplements, it is not a solution used by alone, but needs to be used alongside dietary changes and medications if necessary.
    Yeah that is for sure,i have also tried solgar brand for only one month ,the reason i didnít purchase again just because i didnít find it in my hometown country other than that i think its a good brand


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