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Thread: Vitamin D Bad ?

  1. #1
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    Default Vitamin D Bad ?

    https://www.ncbi.nlm.nih.gov/pubmed/29606809

    Does this mean taking vitamin d could make things worse ?

  2. #2
    Senior Member Brady Barrows's Avatar
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    This paper concludes, "This suggests that the role of vitamin D level in the pathogenesis of rosacea merits further investigation."

    There are papers that say rosaceans have low vitamin D serum levels and there are papers that say rosaceans have high vitamin D serum levels. Wouldn't it be incredible if 10,000 rosaceans got together and agreed to each donate one dollar and sponsor their own double blind, placebo controlled, peer reviewed study on this subject? Would such a miracle ever happen?

    If you go to this page, scroll down to Vitamin D, you can find more information on this controversy about Vitamin D serum levels in rosaceans.
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  3. #3
    Senior Member Tom Busby's Avatar
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    The medical articles seem to be evenly divided as to whether rosaceans have too much or too little Vitamin D. Therefore half of the studies are incorrect, for unknown reasons.

    It also seems that Vitamin D is poorly absorbed in the gut system, for unknown reasons, so an accurate appraisal of supplementation would require weekly blood tests, which is impractical and expensive.

    Intravenous doses of Vitamin D would yield more accurate results, because they would bypass the individual differences in people's gut metabolism. However, this has not been extensively studied, and not at all for rosaceans as far as I can determine. Plus, intravenous is not on anyone's list of things to do.

    Anyway, an oral maintenance dose of 10mg per day (1,000 IU) seems to recommended -- this is the minimal dose. Up to 10,000 IU (100mg) oral supplementation is allowed per day as the upper limit.

    Here's an interesting overview of the benefits, with a very readable format: https://www.rxfiles.ca/rxfiles/uploa...view-QandA.pdf

    My opinion is that a transdermal dose would be more effective because the skin already makes Vitamin D via sunlight on the skin. The problem is that the dose and dosage need to be worked out. Simply making logical assumptions, conservatively low-side, what if the skin is about 100 times more efficient at rendering Vitamin D3 bioavailable (compared to taking oral supplements)? If this assumption is true, then a transdermal oil in water emulsion dose of merely 10 IU (same as 0.1mg) per day would hypothetically deliver the same maintenance-dose as 1,000 IU taken orally.

    Or, what if we assume the skin is 10 times more effective as to bio-availability, compared to oral supplements? Then the transdermal dose would be 100 IU (1mg) per day. The dose is really tiny, so the assumptions are super significant. It's a complicated subject that lacks enough research to be sure.

  4. #4
    Senior Member Mistica's Avatar
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    Personally, I think the studies on vitamin D in nearly all areas of health are flawed as they usually only test 25(OH)D, which is the store form.
    There is no way of knowing if the person is actually not making enough vitamin D from sunlight exposure, or in their diet (which would be minimal unless supplementing), unless the Calcitriol (1,25 dihydroxy-vitamin D) is also tested.
    If a person had increased need for converting D into it's active form, it would be taken from the stores and this would be reflected in lower amounts.

    I have had both tested and the active was slightly elevated.
    Having said all this, seeing doctors rarely test both, the debate of interpretation is probably in it's infancy.
    Previous Numerous IPL.
    Supplements: Niacinamide, Vit K2, low D3, Moderate Dose Vit C, Iodine, Taurine, Magnesium. Very low dose B's. Low dose zinc (to correct deficiency).
    Skin Care: No Cleanser, ZZ cream mixed with Niacinamide gel 4% and LMW HA.

    Treating for gut dysbiosis under specialist care. (This is helping).
    Previous GAPS diet. Testing tolerance of resistant starch.
    Fermented Foods. 2 to 3 days per week, Intermittent fasting -16-18 hours.

  5. #5
    Senior Member Brady Barrows's Avatar
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    Wouldn't it be incredible if 10,000 Rosaceans got together in unity and each donated a dollar so that they could engage in a double blind, placebo controlled, peer reviewed clinical study on Vitamin D and rosacea that these members all agreed would be a study worth sponsoring? How can you get 10,000 rosaceans together in a non profit organization for rosacea that could do this? I suppose you could ask the NRS to engage in such a study but in case you didn't know the NRS spends most of its donated funds on private contractors owned by the president/director of the NRS, Sam Huff. Or you could ask the AARS to engage in such a study, but the vast majority of the donated funds are spent on dermatology conventions for its prestigious members. You could ask the ARSC to engage in such a study since we have no idea what this non profit organization actually spends its money on since Canadian non profits are not required to disclose what it spends its donated funds on. All three non profit organizations for rosacea are created by NON rosaceans. Is there a non profit organization created by rosacea sufferers? There is only one. Do you think it is possible that this non profit organization for rosacea sufferers will ever be able to get 10,000 members together in unity to each donate $1 to engage in Vitamin D/rosacea research or any other rosacea research? Actually the answer is up to you.
    Brady Barrows
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