I’ve taken low dose doxy for probably about three years. It’s the only thing which has kept any rosacea symptoms from recurring. I’ve had no adverse effects during this time. My dermatologist and gp are both happy for me to continue.
Ive tried to wean off it at certain points and rely on other treatments. I just had a period of about a month of not taking it. Symptoms eventually begin creeping back every time though.
For me it seems to keep flushing at bay and my body seems to be better able at tolerating temperature changes, triggers like red wine, etc.
I am conscious of the whole debate around antimicrobial resistance, etc. There are a number of studies out there though which point to long term use of low dose doxy being safe with no long term problems