Page 2 of 4 FirstFirst 1234 LastLast
Results 11 to 20 of 33

Thread: Botox helping my flushing (!)

  1. #11
    Senior Member
    Join Date
    Oct 2015
    Posts
    303

    Default

    Quote Originally Posted by antwantsclear View Post
    Moxonodine often does work better for some, clonidine works better for others, so I wouldn't give up just because clonidine didn't work out for you. I am much happier with moxonodine. Carv. does not work for everyone - only a small number of people are taking this for rosacea.

    No, I didn't find I need to cross taper much if at all between the two alpha blockers - certainly no more than a day of taking clonidine and moxonidine at the same time. You'd need to be careful of low blood pressure as well if you took both at the same time in significant doses.

    By contrast, mirtazapine does often require tapering down very slowly if want to come off it. You can even buy it in an expensive liquid form to make the tapering down process very slow and precise.
    I HATE THIS WEATHER IN THE UK - it is too hot. I can't stop flushing in this heat. I don't know what to try, Prof Chu says there are other meds for me to take...maybe moxonodine will work better? What other ones could I try. Please help. Thank you so much. Feeling horrendous at the moment and so down

  2. #12
    Senior Member
    Join Date
    Aug 2010
    Posts
    1,083

    Default

    Quote Originally Posted by ginaisred View Post
    I HATE THIS WEATHER IN THE UK - it is too hot. I can't stop flushing in this heat. I don't know what to try, Prof Chu says there are other meds for me to take...maybe moxonodine will work better? What other ones could I try. Please help. Thank you so much. Feeling horrendous at the moment and so down
    Higher Nature colloidal silver spray bottles are good - at least you can cool down if you do get a mild flush. But I think the best thing is to try and stay out of the sun. I put mineral water in it if I don't want to buy more of the water, not tap water. Tap water is very irritating to rosacea.

    If your flushing is bad I think you'll need the moxonodine AND a anti malarial, not one or the other.

  3. #13
    Senior Member
    Join Date
    Oct 2015
    Posts
    303

    Default

    Quote Originally Posted by antwantsclear View Post
    Higher Nature colloidal silver spray bottles are good - at least you can cool down if you do get a mild flush. But I think the best thing is to try and stay out of the sun. I put mineral water in it if I don't want to buy more of the water, not tap water. Tap water is very irritating to rosacea.

    If your flushing is bad I think you'll need the moxonodine AND a anti malarial, not one or the other.
    Are there severe side effects with antimalarials? That is what concerns me. Thank you for your help and advice, you are very kind. I find the sun is bad, but it is the heat and humidity so going into a hot car = flush, going into a hot room = flush, undercover on a hot day = flush. Sadly I can't seem to avoid them, but will try the water spray

  4. #14
    Senior Member
    Join Date
    Aug 2010
    Posts
    1,083

    Default

    Quote Originally Posted by ginaisred View Post
    Are there severe side effects with antimalarials? That is what concerns me. Thank you for your help and advice, you are very kind. I find the sun is bad, but it is the heat and humidity so going into a hot car = flush, going into a hot room = flush, undercover on a hot day = flush. Sadly I can't seem to avoid them, but will try the water spray
    Moxonodine has relatively few side effects - especially severe ones, whereas the anti malarials do carry potential side effects. The main possible risk with hydroxychloroquine in long term use is potential vision problems. So yes you definitely need to weigh up the side effects and look out for any side effects if you decide to take them. Mepacrine doesn't seem to carry the vision side effect but is less effective (and harder to get from a pharmacy).

  5. #15
    Senior Member laser_cat's Avatar
    Join Date
    Jan 2017
    Posts
    715
    Country: United States

    Default

    I just got a prescription for plaquenil. Thanks for the tip, antwantsclear.

    (I will start after bloodwork and eye exam.)

    I am still hopeful about switching from clonidine -> moxonidine at some point (the derm I saw did not have knowledge about moxonidine).

    Finally, the derm really suggested I retry propranolol and gabapentin (one at a time for at least 4 weeks) that she has the most luck with those 2 drugs for severe flushing cases. I'm game I guess, but each time I've tried propranolol I find I'm crying half the day LOL for no reason.

    Still maintaining the progress from the botox, except I find I need to sleep a bit upright for ~1 day near ovulation.

    //Lizzy.

  6. #16
    Senior Member
    Join Date
    Oct 2015
    Posts
    303

    Default

    Quote Originally Posted by laser_cat View Post
    I just got a prescription for plaquenil. Thanks for the tip, antwantsclear.

    (I will start after bloodwork and eye exam.)

    I am still hopeful about switching from clonidine -> moxonidine at some point (the derm I saw did not have knowledge about moxonidine).

    Finally, the derm really suggested I retry propranolol and gabapentin (one at a time for at least 4 weeks) that she has the most luck with those 2 drugs for severe flushing cases. I'm game I guess, but each time I've tried propranolol I find I'm crying half the day LOL for no reason.

    Still maintaining the progress from the botox, except I find I need to sleep a bit upright for ~1 day near ovulation.

    //Lizzy.
    Keep me
    Updated. I may have to change my meds as clonidine, carvedilol and mirtazapine are not stopping my flushing. Have made it more manageable but it's still there


    Sent from my iPhone using Tapatalk

  7. #17
    Senior Member laser_cat's Avatar
    Join Date
    Jan 2017
    Posts
    715
    Country: United States

    Default

    Quote Originally Posted by antwantsclear View Post
    Moxonodine has relatively few side effects - especially severe ones, whereas the anti malarials do carry potential side effects. The main possible risk with hydroxychloroquine in long term use is potential vision problems. So yes you definitely need to weigh up the side effects and look out for any side effects if you decide to take them. Mepacrine doesn't seem to carry the vision side effect but is less effective (and harder to get from a pharmacy).
    Hi ants --

    I was wondering if you had experience with plaquenil? I've been on it for 3-4 weeks now, and for the past week I think the flushing/burning is a bit worse ... I've read on the forum that some others had this initial worsening and improved later. I'm on 24,000 mg total / week.

    I'm a bit concerned since plaquenil seems to dampen immune response / lower autoimmune issues and particularly help accutane-induced flushing. But I've never been on accutane, and my inflammatory markers (like C reactive protein) are all normal, if not under-range....

    Of course my recent worsening could be due to something else entirely!

    Thanks for your input,

    Best,

    Lizzy

  8. #18
    Senior Member
    Join Date
    Aug 2010
    Posts
    1,083

    Default

    Quote Originally Posted by laser_cat View Post
    Hi ants --

    I was wondering if you had experience with plaquenil? I've been on it for 3-4 weeks now, and for the past week I think the flushing/burning is a bit worse ... I've read on the forum that some others had this initial worsening and improved later. I'm on 24,000 mg total / week.

    I'm a bit concerned since plaquenil seems to dampen immune response / lower autoimmune issues and particularly help accutane-induced flushing. But I've never been on accutane, and my inflammatory markers (like C reactive protein) are all normal, if not under-range....

    Of course my recent worsening could be due to something else entirely!

    Thanks for your input,

    Best,

    Lizzy
    Hi Lizzy

    I definitely would not give up yet. My experience of plaquenil and others' I've read is that it's often between weeks 8-12 that the best results start to show. Plaquenil is an anti-parasitic so in this sense may have some benefit on the demodex mites as well (but I've not seen clear research on this).

    Other things you can do to maximise the benefits of taking plaquenil would be to use Soolantra cream at the same time or ideally a mix of almond oil/tea tree oil (ratio 4:1) each day to address the mites and just give your skin the best topical treatment possible. Also, and this may seem minor but made a massive change for me, you can avoid showers and putting tap water on your face, taking baths where you don't submerge your head instead but keep it dry. I wash my hair over the sink so the water doesn't touch the face with the shower head, and wash the rosacea affected areas of the face only with mineral water. Although plaquenil can be very helpful for some with rosacea, addressing the topical side as well is important.

    Additionally diet (reducing sugars, and in particular eliminating grains if possible, especially flour/gluten) will have a big benefit.

    To me really there are four aspects to treating rosacea: medical (e.g. oral drugs and creams), alternative medicines/nutrition (e.g. tea tree oil, diet and supplements), topical (e.g. the right water to wash rosacea affected areas and cleanser, if any) and psychological (e.g. a specialist clinical psychologist with an interest in dermatology who can support you through). These things all work in synch with a greater impact than using only one or two of the options (even the most powerful individual options such as plaquenil have limitations when used in isolation).
    Last edited by antwantsclear; 24th August 2017 at 11:43 PM.

  9. #19
    Senior Member
    Join Date
    Aug 2010
    Posts
    1,083

    Default

    Hydroxychloroquine will work best with clonidine OR moxonidine if your flushing is bad, as each performs a different function, the first having an anti-inflammatory impact and the second two being blood pressure medications. The hydroxychloroquine should essentially make your blood vessels look less swollen/reduce facial redness and moxonodine or clonidine reduces the blood pressure (e.g. the pressure of blood to the face/extent of the blood flow at certain times of the day that cause the flushing in response to diet or other triggers).

  10. #20
    Senior Member laser_cat's Avatar
    Join Date
    Jan 2017
    Posts
    715
    Country: United States

    Default

    Quote Originally Posted by antwantsclear View Post
    Hi Lizzy

    I definitely would not give up yet.
    Thanks for your encouraging + thorough response ants! Will definitely keep on the plaquenil, I was just a bit worried!

    I'm still on the clonidine & have been able to resume therapy since I don't need to be near a freezer 24/7 anymore :p I'll think about retrying soolantra & diet changes to see if the combination of everything has an impact

    Thanks again, and I'd bet you know more about this stuff than most derms out there ha.

    //Lizzy

Similar Threads

  1. Botox for flushing
    By geobiders in forum Prescription medications
    Replies: 15
    Last Post: 31st January 2015, 12:57 PM
  2. Botox and flushing?
    By snuffleupagus in forum General rosacea questions
    Replies: 7
    Last Post: 13th June 2009, 07:05 PM
  3. Anyone taken Grape Seed Extract? Might be helping flushing
    By queta in forum Topical and oral products (non-prescription)
    Replies: 24
    Last Post: 2nd April 2008, 12:30 AM
  4. Botox and flushing
    By flushnomore in forum General rosacea questions
    Replies: 3
    Last Post: 9th November 2005, 03:47 AM
  5. More on BOTOX for Rosacea Flushing
    By drnase in forum News, research articles and current affairs
    Replies: 2
    Last Post: 5th July 2005, 05:37 AM

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •