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Thread: KPRF, LRP-1 and Metalloproteinases

  1. #191
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    It arrived today. Took 2 capsules around morning time, and 2 around an hour ago (2100 hours). I'll probably just have 2 capsules a day before bed though. Did anyone else feel hot after taking them? I personally hate this feeling as it always was a symptom of an upcoming flush.

  2. #192
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    Take 3 in the morning on an empty stomach. And 3 afternoon. Do not take at night. Then describe your feelings.

  3. #193
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    @pancakes&syrup,
    How are you now?

  4. #194
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    I think it's too soon to tell. Been taking daily for a week now. 2 at night, and either 1 in morning if not working / 2 in morning if am working (makes stomach a bit dodge). skins gotten oilier, few rashes have appeared - but disappeared quickly. not really noticed any improvement in flushing yet, but had a bad one today - it sucked. mood might possibly be improved, but not sure if placebo. I'll keep at it for now. Cheers.

  5. #195
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    Out of interest, has anyone tried Sage for KPRF?

    I read it helps hot flushes for menopausal women.
    even though I'm a bloke below 30, if it helped i would take it.

  6. #196
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    Right I'm stopping ashwagandha now. Flushing again. Past few flushes have been more severe than in recent times. ****s sake. Gonna try Sage. Does anyone have any experience with Sage?

  7. #197
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    Sage? What is this?

  8. #198
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    It's a herb man, try googling it - there will be plenty of articles on it. Try googling it with the words 'hot flush' as well. I know only taking ashwagandha for a week wasn't long enough - but I was getting bad flushes with it; worse than normal. Trying sage now. If anyone else has tried sage, please give your experience

  9. #199
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    Jun 2015
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    has anyone ever taken rosiglitazone? http://www.ncbi.nlm.nih.gov/pubmed/22889684 study here shows it could upregulate lrp1. Also here: http://www.ncbi.nlm.nih.gov/pubmed/18281370 shows how angiotensin 2, a hormone we have is responsible for upregulation. Maybe figuring out how to increase angiotensin could help our cause?

  10. #200
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    Supposedly waves of hot flushes positively regulates powder MSM. Maybe it is worth a try.
    Last edited by poppe; 17th April 2016 at 09:36 AM.

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