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Thread: KPRF, LRP-1 and Metalloproteinases

  1. #121
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    Quote Originally Posted by darkside View Post
    One of the worst trigger is the warm room thing, so if it improves also that it's great

    I'm evaluating what to order but I'll try Ashwagandha for sure.

    Ideally I would like to try this combo:

    Ashwagandha,
    Turmeric (Curcumin) + quercetin,
    resveratrol + pterostilbene

    I would like to find something against our main problem, the keratin disorders we have. It's genetic but I've also read that can be caused by Vitamin A deficiency..

    Another thing I'm evaluating is Pepcid Complete, that should prevent alcohol flush if taken 40 minutes before a drinking any alcohol. Side effect is that it can slow the breakdown of ethanol, and this can be very dangerous..
    Pepcid AC for the alcohol flush works wonders for me. I usually take it with a small meal about 35 minutes before drinking. I think it can help you get intoxicated faster so be somewhat careful. I have used it multiple times successfully though.

  2. #122
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    Quote Originally Posted by SRT150 View Post
    Pepcid AC for the alcohol flush works wonders for me. I usually take it with a small meal about 35 minutes before drinking. I think it can help you get intoxicated faster so be somewhat careful. I have used it multiple times successfully though.
    That's a great news, hope to try it soon

  3. #123
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    Do any of you used diet? Each of the KPRF here it all? Eggs, fish, meat etc? Rice, noodle, bread?
    Do maybe someone noticed that some foods cause him greater erythema/redness?

  4. #124
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    Quote Originally Posted by Xxcooperxx View Post
    Haven't drank any alcohol yet but warm rooms still get me abit red but not as bad as it use to, it feels like your going a lot redder than you actually are...

    Hi Mate

    Would I be right in saying that this stuff helps with excitement , Stress Flushing ?

  5. #125
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    Quote Originally Posted by davekelly View Post
    Hi Mate

    Would I be right in saying that this stuff helps with excitement , Stress Flushing ?
    Just generally really Dave, main thing I've noticed is when working I get a sweat on I aren't looking as red if that makes sense, but also yea I aren't flushing hardly at all but I do think taking ashwagandha really helps anxiety levels which I can be proned too, I've just ordered another bottle of capsules so going carry on taking them seen as they doing a job, for the price Dave it's worth a try for yourself mate...

  6. #126
    Senior Member Mistica's Avatar
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    Glad to hear that for a couple of people at least, Ashwaghanda is providing flushing reduction benefits.

    Perhaps some of the negatives in the form of feeling unwell, and a bit fluish, are due to the antimicrobial effects?
    Or it could be an adverse immune reaction.

    The reason I am popping back to this thread again, is that I want to update my comments on the supplement NAC.
    To recap, I had taken it in the past when I was a really, really severe flusher, as part of the CAP (Combined Antibiotic Protocol). NAC is included as it supposedly bursts elementary bodies (EBs) of Chlamydia Pneumoniae. This process causes inflammation in the body and is known as the NAC flu.
    I am not sure this has been proven, not to say there isn't any basis for it.

    Anyway, back then NAC made me flush, badly. I was in bad shape in general, with significant gut issues.

    I have tried it since, sporadically, with the same, although less dramatic effect.

    Recently I tried it again. I have hash's and NAC has been known to help alleviate symptoms, as among other things, it helps increase levels of Glutathione, a master antioxidant.
    This time round it has not made me flush. In fact, I am going to cautiously say, I think my face is less reactive and I have been able to get more sleep this past week, and less overnight flushing of my damaged right upper cheek. (brimonidine/oral metro induced).

    There are downsides, however. I have a constant, low grade fluish feeling, which is concentrated from the base of neck upwards. The very back of the roof of my mouth, where the throat begins, feels uncomfortable, a bit inflamed, but not in the same way as a typical sore throat presents. I have a low grade headache and mild earache most of the day.
    My cheek bones ache a bit. Yet, I am paler in general.

    If NAC is having an antimicrobial effect, this should pass, but if it is just an adverse reaction, I'd have to cease taking it. The problem is, trying to establish what is really happening.

    NAC is a high sulphur supplement and as such, modifies gut bacteria. Studies show it to increase levels of lacto and bifido, whilst supporting the integrity of the intestinal lining.
    It is also known for supporting liver function.
    The other most well known use is for it's mucolytic properties and I suppose this might be occurring in my sinuses given the mild, slow drain down the back of my throat. I was not aware of any issues prior, however.
    Cpn is known to concentrate in the sinuses, so if the NAC theory is true, perhaps there is a degree of EB bursting going on there.

    It is all perhaps, perhaps, perhaps.

    Ok, so most of this is irrelevant for KP sufferers, barring the facts that NAC is a proven antioxidant, it protects against lipid peroxidation, and sulphur has therapeutic effects on skin structure.

    As I said, I wanted to pop back and report on my latest experience thus far, so other people can see that experiences can change over time with some supplements.
    In this case my flushing is reduced, but I may stop the the NAC if the negative effects continue.
    I'll update soon.
    Previous Numerous IPL.
    Supplements: Niacinamide, Vit K2, low D3, Moderate Dose Vit C, Iodine, Taurine, Magnesium. Very low dose B's. Low dose zinc (to correct deficiency).
    Skin Care: No Cleanser, ZZ cream mixed with Niacinamide gel 4% and LMW HA.

    Treating for gut dysbiosis under specialist care. (This is helping).
    Previous GAPS diet. Testing tolerance of resistant starch.
    Fermented Foods. 2 to 3 days per week, Intermittent fasting -16-18 hours.

  7. #127
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    I'm quite happy with my appearance for time being so thought I would update with a picture from this morning, best I've been since I realised what I have...
    image.jpg

  8. #128
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    Quote Originally Posted by Xxcooperxx View Post
    I'm quite happy with my appearance for time being so thought I would update with a picture from this morning, best I've been since I realised what I have...
    image.jpg
    Wow what a difference that is from your photo before you started taking it .

    All this progress in less than 3 weeks ? .

  9. #129
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    Quote Originally Posted by Xxcooperxx View Post
    I'm quite happy with my appearance for time being so thought I would update with a picture from this morning, best I've been since I realised what I have...
    image.jpg
    AWESOME mate! I've ordered Ashwagandha and other supplements too ;) pepcid AC requires a medical prescription in my country, I'll look to look for something similar that doesn't need it..

  10. #130
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    Quote Originally Posted by Mistica View Post
    Glad to hear that for a couple of people at least, Ashwaghanda is providing flushing reduction benefits.

    Perhaps some of the negatives in the form of feeling unwell, and a bit fluish, are due to the antimicrobial effects?
    Or it could be an adverse immune reaction.

    The reason I am popping back to this thread again, is that I want to update my comments on the supplement NAC.
    To recap, I had taken it in the past when I was a really, really severe flusher, as part of the CAP (Combined Antibiotic Protocol). NAC is included as it supposedly bursts elementary bodies (EBs) of Chlamydia Pneumoniae. This process causes inflammation in the body and is known as the NAC flu.
    I am not sure this has been proven, not to say there isn't any basis for it.

    Anyway, back then NAC made me flush, badly. I was in bad shape in general, with significant gut issues.

    I have tried it since, sporadically, with the same, although less dramatic effect.

    Recently I tried it again. I have hash's and NAC has been known to help alleviate symptoms, as among other things, it helps increase levels of Glutathione, a master antioxidant.
    This time round it has not made me flush. In fact, I am going to cautiously say, I think my face is less reactive and I have been able to get more sleep this past week, and less overnight flushing of my damaged right upper cheek. (brimonidine/oral metro induced).

    There are downsides, however. I have a constant, low grade fluish feeling, which is concentrated from the base of neck upwards. The very back of the roof of my mouth, where the throat begins, feels uncomfortable, a bit inflamed, but not in the same way as a typical sore throat presents. I have a low grade headache and mild earache most of the day.
    My cheek bones ache a bit. Yet, I am paler in general.

    If NAC is having an antimicrobial effect, this should pass, but if it is just an adverse reaction, I'd have to cease taking it. The problem is, trying to establish what is really happening.

    NAC is a high sulphur supplement and as such, modifies gut bacteria. Studies show it to increase levels of lacto and bifido, whilst supporting the integrity of the intestinal lining.
    It is also known for supporting liver function.
    The other most well known use is for it's mucolytic properties and I suppose this might be occurring in my sinuses given the mild, slow drain down the back of my throat. I was not aware of any issues prior, however.
    Cpn is known to concentrate in the sinuses, so if the NAC theory is true, perhaps there is a degree of EB bursting going on there.

    It is all perhaps, perhaps, perhaps.

    Ok, so most of this is irrelevant for KP sufferers, barring the facts that NAC is a proven antioxidant, it protects against lipid peroxidation, and sulphur has therapeutic effects on skin structure.

    As I said, I wanted to pop back and report on my latest experience thus far, so other people can see that experiences can change over time with some supplements.
    In this case my flushing is reduced, but I may stop the the NAC if the negative effects continue.
    I'll update soon.
    Thanks for sharing

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