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Thread: Seborrheic Dermatitis & Folliculitis -- Review of OTC Treatments for Malassezia

  1. #11
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    I know you use/d Nizoral cream on your face and am wondering if you have tried Lotrimin Ultra?

    According to Jeff's research azoles interfere with yeast growth but don't do much to kill existing yeast wheres allylamines kill live yeast. In my experience Butenafine (an allylamine available in Lotrimin Ultra) is more effective than Ketoconazole (an azole available in Nizoral cream). Unfortunately Butenafine is not available in Australia and although I import it via eBay, I mostly rely on Nizoral. Interestingly, Turbenafine is useless on my face but reasonably effective in my groin area. Perhaps because it's a different strain of Malassezia, or the biofilm is less entrenched?

    I'm interested in your thoughts... Lotrimin Ultra is OTC in the US, perhaps you have been down this path already?

  2. #12
    Senior Member Tom Busby's Avatar
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    I never used Lotromin Ultra so I can't say from my own experience. I was glad to see that Jeff found it worked and posted his results.

    I did try Lotromin AF fairly early-on in my attempts to find a treatment and it did nothing at all. I wish I would have tried Lotromin Ultra, and I think I'll try it now, although I'm almost at complete cure so it will not be a very conclusive test.

    The manufacturer's website has a $2 off coupon too.

  3. #13
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    My story has been created and if I start with Toms recommendations my progress will be In that thread.

    http://www.rosaceagroup.org/The_Rosa...ions-Questions

    Any suggestions would be appreciated.

  4. #14
    Senior Member Tom Busby's Avatar
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    Hereís a cool looking new product that daneel just posted about -- Bioderma Sensibio Foaming Gel, with climbazole, piroctone olamine and xylitol. This should be very effective, and other reviewers say it smells great too. I had never heard of it before.

    Hereís a link from Amazon to order a giant sized 500 ml bottle that ships from Portugal: http://www.amazon.com/gp/offer-listi...&condition=all

  5. #15
    Senior Member Tom Busby's Avatar
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    Another new shampoo containing 0.5% piroctone olamine and 0.45% climbazole is made by Eucerin, and is called DermoCapillaire Antidandruff Gel Shampoo.

    It's also the subject of a 2013 medical research article, "Highly Efficient Rinse-Off/Leave-On Scalp Care Treatments to Reduce Moderate to Severe Dandruff," and posted at: www.scirp.org/journal/PaperDownload.aspx?paperID=26935‎.

    Itís currently sold only on Amazon and eBay as far as I can tell.

  6. #16
    Senior Member Mistica's Avatar
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    Default Biofilm buster - Zymox

    I posted about the benefits of lactoferrin a while back.



    Here is an enzymic solution which contains the following ingredients:


    Lactoferrin

    Lactoperoxidase

    Lysozyme


    It is actually a product for dogs for treatment of yeast/fungal ear infections.
    I use it on my dog. He is healthy, but from time to time, he gets a mild ear infection. I wanted to avoid the steroids that most vets prescribe.
    Zymox comes with or without hydrocortisone. I use the one without.
    It works very well. I have only needed to use it a couple of times, where as with the traditional steroid treatment, the symptoms kept returning, although it was never a major infection.

    Given the fact Tom and others here are very interested in biofilm busters, I thought I would throw this option into the mix.

    http://www.vetinfo.com/zymox-otic-for-dogs.html
    Previous Numerous IPL.
    Supplements: Niacinamide, Vit K2, low D3, Moderate Dose Vit C, Iodine, Taurine, Magnesium. Very low dose B's. Low dose zinc (to correct deficiency). Tocotrienols.
    Skin Care: No Cleanser, ZZ cream mixed with Niacinamide gel 4%.

    Treating for gut dysbiosis under specialist care. (This is helping).
    Previous GAPS diet. Testing tolerance of resistant starch.
    Fermented Foods. Daily Intermittent fasting -16-18 hours.

  7. #17
    Senior Member Tom Busby's Avatar
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    I realized that such tiny amounts of Climbazole are effective, that 10 ml of Hegor 150 shampoo can be added to 200 ml of lotion, which will be equivalent to my home compound from Climbazole powder. My suggestion for a Hegor 150 is because most people donít want to buy Climbazole powder and dissolve it.

    Currently Iím using this very effective lotion:
    180 ml Cetaphil lotion
    20 ml distilled water
    0.4 ml Propolis
    0.4 ml Farnesol
    0.6 grams Citric Acid
    4.0 grams Xylitol
    4 grams Aquaphor
    0.14 grams Climbazole dissolved in 1 ml Isopropanol (equivalent to 10 ml of Hegor 150 in 200 ml of lotion)

    Mix the Citric Acid and Xylitol into 20 ml of water in a shot glass, and then pour it into the lotion. Heat 4 grams Aquaphor to 120 degrees in hot water, remove and blend with an equal amount of lotion, stir, and pour back into 180 ml of lotion. Pour everything else into the lotion and shake well. The measured pH is 3.5. The low pH doubles the effect of the Climbazole.

  8. #18
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    Quote Originally Posted by Tom Busby View Post
    I realized that such tiny amounts of Climbazole are effective, that 10 ml of Hegor 150 shampoo can be added to 200 ml of lotion, which will be equivalent to my home compound from Climbazole powder. My suggestion for a Hegor 150 is because most people donít want to buy Climbazole powder and dissolve it.

    Currently Iím using this very effective lotion:
    180 ml Cetaphil lotion
    20 ml distilled water
    0.4 ml Propolis
    0.4 ml Farnesol
    0.6 grams Citric Acid
    4.0 grams Xylitol
    4 grams Aquaphor
    0.14 grams Climbazole dissolved in 1 ml Isopropanol (equivalent to 10 ml of Hegor 150 in 200 ml of lotion)

    Mix the Citric Acid and Xylitol into 20 ml of water in a shot glass, and then pour it into the lotion. Heat 4 grams Aquaphor to 120 degrees in hot water, remove and blend with an equal amount of lotion, stir, and pour back into 180 ml of lotion. Pour everything else into the lotion and shake well. The measured pH is 3.5. The low pH doubles the effect of the Climbazole.
    That's a powerful mix, Tom. Perhaps you should patent this? It looks a darn sight more effective than other lotions I've been handed at my derm's.

    Unfortunately, Hegor 150 shampoo contains the ingredient Cocomidopropyl Betaine, so I can't use it without getting contact dermatitis. I may try Climbazole powder instead.

    However, I do notice that Xylitol causes dermatitis on the day I apply it as well but this seems to disappear overnight, so it might be the same with Hegor shampoo. I could probably handle that if the reaction is short-lived.

  9. #19
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    Thanks Tom, I'm going to give this a go... I'll use the Hegor 150 and add propolis and farnesol when they come to hand.

    I suppose I could make a similar lotion for my face using Nizoral shampoo? I expect this would be more effective and less expensive than the 30ml tubes which don't last long.


    Quote Originally Posted by Tom Busby View Post
    I realized that such tiny amounts of Climbazole are effective, that 10 ml of Hegor 150 shampoo can be added to 200 ml of lotion, which will be equivalent to my home compound from Climbazole powder. My suggestion for a Hegor 150 is because most people donít want to buy Climbazole powder and dissolve it.

    Currently Iím using this very effective lotion:
    180 ml Cetaphil lotion
    20 ml distilled water
    0.4 ml Propolis
    0.4 ml Farnesol
    0.6 grams Citric Acid
    4.0 grams Xylitol
    4 grams Aquaphor
    0.14 grams Climbazole dissolved in 1 ml Isopropanol (equivalent to 10 ml of Hegor 150 in 200 ml of lotion)

    Mix the Citric Acid and Xylitol into 20 ml of water in a shot glass, and then pour it into the lotion. Heat 4 grams Aquaphor to 120 degrees in hot water, remove and blend with an equal amount of lotion, stir, and pour back into 180 ml of lotion. Pour everything else into the lotion and shake well. The measured pH is 3.5. The low pH doubles the effect of the Climbazole.

  10. #20
    Senior Member Tom Busby's Avatar
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    The problem with Ketoconazole is that it requires at least a 1% concentration in lotions and so it costs a lot more than Climbazole, which is effective at 0.07%. Also, Ketoconazole has feminizing properties. PM me if you want to buy 98% Climbazole powder. I'm not sure exactly how this works in Canada but I might be able to provide some info that helps.

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