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Thread: Low Dose Naltrexone..

  1. #1
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    Default Low Dose Naltrexone..

    I have been reading a lot lately about Low Dose Naltrexone. Has anyone tried this? Supposedly it has helped people with Autoimmune disorders like Lupus, IBS, Crohns, etc and many cancers. People with these diseases have very low endorphin levels. And once they start taking the low dose Napltrexone they get much better as it raises your endorphin levels 200-300%.

    So it got me wondering if people with Rosacea have very low endorphin levels. High levels of endorphins helps with pain, reduces inflammation, strengthens your immune system, etc etc.. Maybe the burning we experience would go away if we raised our endorphin levels?? Is there a test to measure your endorphin levels?

    As we all know steroids (immunosuppressant’s) make Rosacea a lot worse. So what if we did the opposite and took immunostimulants (Low dose naltrexone). I found the following quote:

    "Low dose naltrexone acts as an immunostimulant, which may seem like a weird choice to use as a treatment in autoimmune illnesses, as they have been generally seen as manifestations of an overactive immune system and are usually treated with immunosuppressants. However more and more data is emerging that suggests that autoimmune conditions may in fact be forms of immunedeficiency. That may explain why LDN works so well for them. It may well be that underactive/overactive are oversimplifications for defining something as complex as the immune system."

    It is a very interesting subject and I am including a few links for everyone to read on the subject. Please read them and let me know your thoughts!!!


    http://www.lowdosenaltrexone.org/#Wh...ose_naltrexone

    http://www.fiikus.net/?ldn

    http://www.radiantrecovery.com/chemistry.htm

    http://www.nutritional-healing.com.a...n%20deficiency

    http://www.road-to-health.com/64/Wha...dorphins_.html

    www.ldninfo.org
    Doug

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    I believe a lot of women get Rosacea when they hit menopause and I just read this..

    "Results: a significant lowering of beta-EP (endorphins) at menopause"...

    interesting...
    Doug

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    Default Black Seed

    Explains why Nigella Sativa relieves Rosacea symptoms doesn't it.....?

    Of course it is part of a complete process of Omega 3 balance, adequate Vitamin D levels and then the healing power of the "blessed seed". I have been clearing up my over 30 years of spider veins and blotches by rubbing on the oil. Take two tablespoons internally daily for overall health.....and the anti wrinkle moisturizer part isn't to bad of a side effect for those of us aging a little.....

    Happy reading on this one, big Pharma ain't gonna like this.

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    As someone who recently got out of the habit of *ahem* supplementing endorphins via opiods (oxycodone mostly)...

    I can honestly say that whenever I was under the influence, my rosacea seemed to be practically nonexistant. I mean, some diffuse redness was still there, but it was reduced by 70% or so...

    I would still flush from the usual triggers though.

    I also took a medication which contained naltrexone in ample quantities (suboxone) and it made very little difference.

    Take it for what its worth I guess...

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    Also, not trying to discredit OP... but naltrexone is well known as an opiod receptor antagonist.

    How would something that blocks binding sites raise endorphin levels?

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    Quote Originally Posted by NotPissedJustFlushed View Post
    As someone who recently got out of the habit of *ahem* supplementing endorphins via opiods (oxycodone mostly)...

    I can honestly say that whenever I was under the influence, my rosacea seemed to be practically nonexistant. I mean, some diffuse redness was still there, but it was reduced by 70% or so...

    I would still flush from the usual triggers though.

    I also took a medication which contained naltrexone in ample quantities (suboxone) and it made very little difference.

    Take it for what its worth I guess...
    Im guessing you were taking much higher levels for your **ahem**....but for what I am talking about you take much less. For example, naltrexone to treat **ahem** you would take around 50mg per day.. for what I am talking about you only take 4.5mg per day. it reacts differently at a low dose...
    Doug

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    Default Low Dose Naltrexone and Inflammation

    Found this online...

    "An amazing new treatment for inflammation, whose results have been miraculous for some of Dr. Singleton's patients, is low-dose Naltrexone. The recommended dose is 4.5 mg. This drug functions by blocking opiod (endorphin) receptors so that the body is fooled into thinking that it needs to produce more endorphins. The result is an increased number of endorphins, which have powerful immune system regulating effects, which includes reducing the body's inflammatory response when it is in overdrive.

    Furthermore, over time, this supposedly side-effect free drug trains the body to make an appropriate amount of endorphins, so that at some point, the sufferer no longer needs the drug to control inflammation.


    Very interesting... i like the part where it reduces the body's inflammatory response when its in overdrive... Sounds like it just might help Rosacea...
    Doug

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    Default Re: Low Dose Naltrexone and Inflammation

    Hi all,
    I have just started on a course of LDN (yesterday) having been through all the usual accepted treatments with limited or no success. I was originally diagnosed about four years ago, and was prescribed Erythromycin and Stiemycin topical solution. I wasn't too keen on taking antibiotics on a long-term basis, and the topical solution made my skin dry and flaky. A second dermatologist recommended vitamin C cream, and that I should look at laser treatment. I decided to investigate how much my diet was contributing to the condition (aside from the usual trigger foods which were obvious), and I went to see a specialist who treats skin conditions and allergies. He put me on an elimination diet which worked wonders - my face cleared up a lot, no bumps and postules, and the redness calmed down immensely. We started to re-introduce foods bit by bit, but so far I have not had any huge flare-ups as I have been avoiding eating any processed or starchy foods, and hardly any sugary foods. There is still a little inflammation there however, but definitely nothing like it was. He has now started me on 3mg of LDN since last night, and will up this to 4.5mg in 6 weeks or so. He says that he has two patients on it who have seen fantastic results. Anyhow, I'm not sure how long it will take to kick in, but I'll keep you posted on whether or not there are any improvements. It would be great if this did the trick as I am so sick of people asking me if I have been out in the sun!

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    Mcreed,

    I just started taking LDN myself. I too am hoping it works wonders. Did your doctor say how long it took the other 2 people he put on LDN to start seeing results? Ive read it can take 3-6 months for skin issues to see results when on LDN.
    Doug

  10. #10
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    Extremely interesting, just read a few articles on LDN released in the past 2 weeks - keep us up to date Smoof.

    Are you on the 4.5mg. dose? What was the ease or difficulty in getting a Script for it? How about cost?? Best of luck with it..

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