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Thread: Positive results from Ivermectin Trial

  1. #1
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    Default Positive results from Ivermectin Trial

    I have been on an Ivermectin trial for just over a week now with quite positive results. I have moderate Rosacea with frequent papules and pustules. My most recent flare up started in July and had continues until this week when I started the topical Ivermectin.

    My skin had improved a little after I started applying Megan Gales Invisable Zinc about a month ago but the change in the last week has been quite dramatic.

    My skin is still far from perfect but as the trial goes for about a year I hope it continues to improve. Initially I was getting about 20 papules on EACH cheek, forehead and even on my neck, so it was pretty ugly, the inflammation was not pleasant either.

    I have the occassional papule left, the worst place is still on my neck but the texture of my skin is soft, no burning or itching and life is a hell of a lot more pleasant. My 3 year old son hasn't been patting my cheek and asking me if it still hurts this week either.

    Looks like those beastly mites have a lot to answer for in my case.

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    what is the dosage you are on? I've tried for and been rejected a prescription of invermectin, as here in the UK GP's don't prescribe it to humans, unless exceptional circumstances require it.

    I have thought about ordering this from one of those online pharmacies.

    Terry

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    I have no idea as it is a trial drug with limited discriptions on the packaging. It is a 30 gram tube with what I presume is 1% Ivermectin. Good luck.
    I have heard that it is commonly used in the states orally for Scabies infestations. We use it here in Australia on dogs with Mange. That was the only info that I could previously get on it.

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    Senior Member Mistica's Avatar
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    Default rachzon

    I am really pleased for you and hope things continue to improve.

    You have mentioned your worse symptoms were P&P's, but did you have much over all redness and/or flushing?

    It is a pity the trial didn't include both types of rosacea, so a better perspective could be made as to what the root cause is.

    By the way, what was the derm like?
    Previous Numerous IPL.
    Supplements: Niacinamide, Vit K2, low D3, Moderate Dose Vit C, Iodine, Taurine, Magnesium. Very low dose B's. Low dose zinc (to correct deficiency).
    Skin Care: No Cleanser, ZZ cream mixed with Niacinamide gel 4% and LMW HA.

    Treating for gut dysbiosis under specialist care. (This is helping).
    Previous GAPS diet. Testing tolerance of resistant starch.
    Fermented Foods. 2 to 3 days per week, Intermittent fasting -16-18 hours.

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    Hi Mistica,
    I flush or blush a lot esp in stressful situations but I always have done. I have always had a tendency to be pinkish as well. I only have a few small broken capillaries around my nose. I suppose because I have always been that way I had excepted that I would never have a peaches and cream complexion. As a teen I was plagued be acne and pimples as well. I grew up in the Northen Territory on the beach with no hat and no sunscreen. Consquently have a lot of sun damage. I always had a tan and didn't notice I was pinkish until I started covering up ( I still spend a lot of time in the sun as we are an outdoor family)So I have never had perfect skin and have accepted that I won't have a very long time ago. My aim with all of this is to be P&P free and have skin that feels comfortable.
    When I have a face full of P&P's my face burns, I flush more easily and it is very painful. I still haven't worked out what comes first whether I start flushing to cause the P&P's or what happens. They just sort of start to appear in mass and life just declines from there. For the last 5 years or so I have never been completly clear of the P&P's but I can tolerate a few.
    The theory behind the Ivermectin is that it doesn't cure the Rosacea it just kills the mites that inflame it. Some of that inflammation process is the appearance of P&P's so I suppose that is why they want a specific group. This trial is also to determine if there is sytematically any long term side effects on the body if you use it for a long time. I have to have regular blood tests. Of course they are still looking at the effect on the Rosacea symptoms.
    I'm supposing that by decreasing the inflammation that you decrease the progression of the Rosacea (is that right?) and then the need for more dramatic therapies. Finding what works is such a battle.

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    The Derm seemed ok. I have had more to do with the Nurse who is lovely. He pops in answers the questions has a look at my skin and leaves again. He did say though that if I had continued to have problems with my Rosacea that he felt there were a few more things we could try. He seemed very approachable. Over all I would be happy to see him for treatment. Did you see my other post on the Greenslopes Clinic?

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    Senior Member Mistica's Avatar
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    Hmmm, I am not sure if I saw the post about Greenslopes or not. It rings a bell, but the data might have become lost in the depths of my dusty cerebral archives. Too much going on in there
    Perhaps you could refresh my memory?

    I really wish you success with the topical Ivermectin. Without any nasty side effects.

    Did the derm mention to you, why they prefered to trial a long term usage of a topical, rather than a few doses of oral?
    Previous Numerous IPL.
    Supplements: Niacinamide, Vit K2, low D3, Moderate Dose Vit C, Iodine, Taurine, Magnesium. Very low dose B's. Low dose zinc (to correct deficiency).
    Skin Care: No Cleanser, ZZ cream mixed with Niacinamide gel 4% and LMW HA.

    Treating for gut dysbiosis under specialist care. (This is helping).
    Previous GAPS diet. Testing tolerance of resistant starch.
    Fermented Foods. 2 to 3 days per week, Intermittent fasting -16-18 hours.

  8. #8
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    Mistica I have just sent you a personal message about the Greenslopes Clinic.

    The nurse seemed to think that if they are getting result topically there is no point in treating your whole system. You can never rid yourself completely of the mite anyway. It is just to control it's population especially if you have Rosacea. It is not a cure for Rosacea but a way to control one of the aggravating factors.

  9. #9
    Moderator Melissa W's Avatar
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    I was exposed to scabies at the health clinic where I work a while ago so my friend who's a doctor put me on the oral ivermectin vs the topical as he said it has less side effects and is easier as well but that was just for two doses of course. Not for regular use. But my friend who is exposed quite a lot to scabies and other such diseases takes Ivermectin on a more regular basis and he always takes the oral ivermectin as opposed to the topical and never had a problem.

  10. #10
    Senior Member Mistica's Avatar
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    Rachel,

    I just called that derm you mentioned. Dr Cominos and was told she is booked until May next year, but after chatting to the receptionist, she said, if I can get a referral and get it faxed through, she will discuss my case with the doc and hopefully she will see me sooner. Hopefully much sooner.
    Meanwhile I called my GP's clinic and spoke to his receptionist and she told me she will ask him, but he will probably refuse. If he does, I will find another GP, but it still means a trip out, needing to hire a car, as we don't have air con and getting my partner out of work as I can't drive. Which will turn my increasingly painful and red face into a huge flare! He already knows I have rosacea ( even though he doesn't understand it), so he ought to just write me a referral.
    Damn doctors.

    Melissa,

    Did you have rosacea when you took the two doses of Ivermectin? If so, did you notice any improvement or worsening of symptoms? Or no change at all?
    Previous Numerous IPL.
    Supplements: Niacinamide, Vit K2, low D3, Moderate Dose Vit C, Iodine, Taurine, Magnesium. Very low dose B's. Low dose zinc (to correct deficiency).
    Skin Care: No Cleanser, ZZ cream mixed with Niacinamide gel 4% and LMW HA.

    Treating for gut dysbiosis under specialist care. (This is helping).
    Previous GAPS diet. Testing tolerance of resistant starch.
    Fermented Foods. 2 to 3 days per week, Intermittent fasting -16-18 hours.

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