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Thread: Mystery solved: rosacea's cause uncovered

  1. #331
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    Quote Originally Posted by buratino29 View Post
    Thanks for info. I will try to get it. I would not recommend to use it orally as it effects not only face but other organs.
    Couple of days ago I started applying cromolyn sodium in nasalcrom form. We know the same university is testing it on patients.
    In a few weeks time I will post my opinion on this.
    So you are applying a cromolyn sodium spray topically?

    Please do post about the results. I'd be curious as I'm taking cromolyn sodium orally and could probably get a prescription for a spray.

  2. #332
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    Here is my resume on Cromolyn sodium.
    Into second week of applying it I noticed my cheeks in calm condition, usually late in the evening, appeared to be brighter than my chin. Since my chin never flushes, I wasnít touching it. So, cautiously I would say it helps to reduce redness. But it didnít do anything against flushing after 3 weeks. Only when the flushing is gone, in calm condition cheeks look brighter than usual.
    It could be that they are testing stronger or more pure compound. I also think it could be absorption problem. After applying it, face looks like with layer of wax. So, clearly a big part of liquid doesnít go through the skin. I also noticed, that if I apply it in the morning just before going out, that wax aggravates rosacea. I found it better to apply in the evening and wash the face in the morning.
    In current form I donít think Cromolyn gives enough benefits.

  3. #333
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    Quote Originally Posted by buratino29 View Post
    Where to buy aminocaproic acid online without prescription in liquid form?
    http://www.ebay.co.uk/itm/Aminocapro...item3f2de5df93

    I am not going to try it myself Too many other things going on...

  4. #334
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    Quote Originally Posted by patty View Post
    Totally agree. Maybe this discovery will inspire them to do more research.
    Do they know there is a pot of gold for the one who comes up with "the cure?"
    Yeah it seems as though this one small study sparked a lot of interest, hopefully confirmation studies will show the same thing! Also, it would be nice to see a real cause and effect relationship.

  5. #335
    Senior Member fauxmccoy's Avatar
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    Default Clinical Study Now Recruiting

    http://www.clinicaltrials.gov/ct2/sh...ea+ucsd&rank=2

    more of Dr. Gallo's work and they are currently recruiting. since i live in northern california, i emailed the contact for this study to let them know that i was interested in participating in this as well as any further studies regarding the topical treatment with aminocaproic acid. will keep folks here informed as to what i learn, if anything

  6. #336
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    Quote Originally Posted by fauxmccoy View Post
    http://www.clinicaltrials.gov/ct2/sh...ea+ucsd&rank=2

    more of Dr. Gallo's work and they are currently recruiting. since i live in northern california, i emailed the contact for this study to let them know that i was interested in participating in this as well as any further studies regarding the topical treatment with aminocaproic acid. will keep folks here informed as to what i learn, if anything
    http://members.irosacea.org/topic/19...osacea/?p=2727

    Mast Cells are Key Mediators of Cathelicidin Initiated Skin Inflammation in Rosacea.
    J Invest Dermatol. 2014 May 20;
    Authors: Muto Y, Wang Z, Vanderberghe M, Two A, Gallo RL, Di Nardo A
    ...
    Our data was confirmed on Erythematotelangiectatic rosacea subjects that showed a decrease in MMP activity (P<0.05), after eight weeks of topical cromolyn treatment. We conclude that MCs play a central role in the development of inflammation subsequent to Cath LL-37 activation and that down regulation of activated MCs may be a therapy for rosacea treatment

    Thanks to Barry for making this highlighted inthis post: http://www.rosaceagroup.org/The_Rosacea_Forum/showthread.php?31190-Topical-Cromolyn-Treatment-for-Rosacea

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