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  1. Replies
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    I take 80 mg cymbalta right now. 80 mg wasn't any...

    I take 80 mg cymbalta right now. 80 mg wasn't any better than 60 mg though. For neuropathic pain I'm told cymbalta / SNRI's are similar to amitriptyline, except they have less side effects. Though...
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    Chai - one time when i tapered off cymbalta, I...

    Chai - one time when i tapered off cymbalta, I did not notice any worsening until about 1 month later.

    I'm guessing possibly downstream effects from the cymbalta might have taken some time to...
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    Not social anxiety but general depression. I have...

    Not social anxiety but general depression. I have a severe case of rosacea. I take antidepressants which help mental health for me a lot. I've also tried ketamine which for was the best out of...
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    How is the taper going? Mirtazapine for me...

    How is the taper going?

    Mirtazapine for me offers some vasoconstriction (mild) proportional to dose. It is subtle but if I forget a pill at night (I take 22.5 mg) then I will have rebound...
  5. Are you on pills? I did a very slow taper where I...

    Are you on pills? I did a very slow taper where I was shaving off a little bit each decrement. Took maybe 2 months? I rebounded a little with some decrements and didn't move down until i was sure the...
  6. I might have had a similar experience with...

    I might have had a similar experience with clonidine.. I did get rebound coming off of it, but I'm better off without it in regards to my flushing.

    I think sometimes people can't handle...
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    [quote=Ange4;350719] Hi Angela - Sorry about...

    Hi Angela - Sorry about that!

    The PEA helps me with baseline burning only like 10%. Certainly within 2 wks.

    I did 3 SG blocks, and none of them were helpful beyond maybe 8 hrs (and they only do...
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    I hope it goes well with the gabapentin, + that's...

    I hope it goes well with the gabapentin, + that's great you were able to find a good dose again with the LDN.

    Everyone is a little different I think but for me + I think others, we've learned...
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    That's great - I'm glad the LDN and amit. and...

    That's great - I'm glad the LDN and amit. and clonidine are helping you.

    FWIW I was on plaquenil for 1-2 yrs and had no side effects (if anything, it helped with occasional joint pain and...
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    I flare (a pulsing style flushing, swelling,...

    I flare (a pulsing style flushing, swelling, burning) or if I'm already flaring have increased flaring. I think my sensory nerves are overly activated (heat, "time of day" flaring) as well as...
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    Hey Angela, I'm not taking THC currently (when...

    Hey Angela,

    I'm not taking THC currently (when I did, it actually wasn't synthetic .. but I don't think that matters.) I am not taking it because of cognitive side effects.

    When I took it, I do...
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    That's great you find gabapentin helpful. I might...

    That's great you find gabapentin helpful. I might retry it. I have tried it in the past and it caused increased blood pooling for me. But possibly I could handle it better now. Even though I didn't...
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    I'm so sorry you are struggling, Angela. I don't...

    I'm so sorry you are struggling, Angela. I don't think the PEA supp will make or break anything for you unfortunately if the CBD did not help at all. They are comparable in mechanism. The PEA helps...
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    update: mexiletine, opioids, etc.

    Been a while so thought I'd come back and share.

    *I've been ramping up very slowly on mexiletine, incrementing about 150 mg / mo. Now at 600 mg. This has been helpful for night flares and...
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    Thank you - even though my nose has gotten a lot...

    Thank you - even though my nose has gotten a lot better (knock on wood ..) I will try the Nasalcrom for a longer time frame and 4x/day.

    I've tried gastrocrom (I think nalcrom?) and it didn't do...
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    Although I am a pain-sensitized patient, I think...

    Although I am a pain-sensitized patient, I think for refractory flushers who might not be pain-sensitized, they might also benefit from agents that target the neuronal control of blood vessels.
    ...
  17. For me I would have rebound on the days I don't...

    For me I would have rebound on the days I don't take it. But check w/ your doc and it may depend on the person. I currently take the IR as needed - this means about 2x / wk.
  18. Peak blood levels with the ER occur at ~6 hrs...

    Peak blood levels with the ER occur at ~6 hrs after taking the pill. My experience with the ER is that it does take time to build up in the system - like 1-2wks of taking 60 mg ER daily. My doc told...
  19. botox typically kicks in 1-2 wks for me. This is...

    botox typically kicks in 1-2 wks for me. This is for baseline redness, afternoon episode, and evening episode. At my most recent appt my derm said botox would not help with social flushing (I had...
  20. I just don't touch my face and take ibuprofen for...

    I just don't touch my face and take ibuprofen for the extra inflammation-induced pain I get. GOod luck!
  21. I would have no problem covering with makeup...

    I would have no problem covering with makeup after maybe 4 days (i just personally do not tend to wear makeup). When I have lots of little injections everywhere, downtime is the longest (1 wk). I...
  22. I don't really have a sense about this. It takes...

    I don't really have a sense about this. It takes about a wk for me to heal from botox, although that does depend on the number of injections.

    I'm also in the US and btw moxonidine is not...
  23. I still do botox and find it specifically...

    I still do botox and find it specifically (partially) helpful for "time of day" flushing. Not at all helpful for anxiety flaring unfortunately.
  24. I personally found 60 mg propranolol ER / day or...

    I personally found 60 mg propranolol ER / day or higher to specifically help with social / anxiety flushing/burning for me, maybe 90%+. Unfortunately that wasn't one of my goals really ("time of...
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    I do not take the buprenorphine currently due to...

    I do not take the buprenorphine currently due to side effects (brain fog) though I admittedly I never tried to see if I could get away with the smallest dose possible. I do not take LDN currently...
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