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New data suggests that an oral drug currently used in the clinical setting to treat neuromuscular diseases could also help prevent a common form of skin cancer caused by damage from ultraviolet-B...

Immune checkpoint inhibitors are life-saving therapies against advanced cancer, but they can cause side effects, most commonly involving the skin. New research provides insights on the extent of...

The ability of HDL particles (commonly known as 'good' cholesterol) to reduce inflammation in the cells that line blood vessels may help predict who is more likely to develop a heart attack or other...

This paper published in the Journal of Cosmetic Dermatology details a clinical trial to prove that 3 products from LETI Pharma are able to reduce the redness of rosacea. The study was supported by...

Rosacea is a common and chronic inflammatory skin disease that is characterized by dysfunction of the immune and vascular system. The excessive production and activation of kallikerin 5 (KLK5) and...

The millions of people who have chronic sinusitis deal not only with stuffy noses and headaches, they also commonly struggle to focus, and experience depression and other symptoms that implicate the...

The millions of people who have chronic sinusitis deal not only with stuffy noses and headaches, they also commonly struggle to focus and experience depression and other symptoms that implicate the...

A new analysis of lung epithelial cells from COVID-19 patients reveals how the protective complement branch of the immune system, which usually plays roles in both innate and adaptive immunity, can...

Cancer doctors may soon have a new tool for treating melanoma and other types of cancer, thanks to work being done by researchers at the University of Colorado Cancer Center.

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An interesting graphic emerged from a recent presentation from Menlo Therapeutics, the owners of the recently approved rosacea treatment Zilxi. Menlo quote from statistics showing the typical growth...

A biomedical engineer is reporting a new deep neural network architecture - to be used on a standard laptop - that provides early diagnosis of systemic sclerosis (SSc), a rare autoimmune disease...

Researchers have discovered that Streptococcus pyogenes, a species of bacteria that can cause severe illness if it invades the human body, can survive on the skin using arginine as a source of...

Here's the most clicked-on item we featured from NEJM Group this week, in case you missed it the first time around: NEJM Resident...

The Hippo signaling pathway plays a key role in regulating organ size and tissue homeostasis. Hippo and two of its main effectors, yes-associated protein (YAP) and WWTR1 (WW domain-containing...

Researchers have found that a widely available and inexpensive drug targeting inflammatory genes has reduced morbidity and mortality in mice infected with SARS-CoV-2, the virus that causes COVID-19. ...

A research team has developed a novel skin-mounted sticker that absorbs sweat and then changes color to provide an accurate, easy-to-read diagnosis of cystic fibrosis within minutes.

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Mast cells are tissue-resident innate immune cells known for their prominent role in mediating allergic reactions. MAS-related G-protein coupled receptor-X2 (MRGPRX2) is a promiscuous G-protein...

Research led by Michigan Medicine's Scleroderma Program and published in Arthritis & Rheumatology found that tocilizumab, a FDA-approved anti-inflammatory drug used to combat rheumatoid arthritis,...

Primary sclerosing cholangitis (PSC) is a rare, chronic, inflammatory disease of the bile ducts and is difficult to treat, since its causes have not yet been adequately researched.

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Primary sclerosing cholangitis (PSC) is a rare, chronic, inflammatory disease of the bile ducts and is difficult to treat, since its causes have not yet been adequately researched. An international...

Psoriasis is a chronic disease that causes patients to develop patches of dry, scaly, and itchy skin. It is an autoimmune disorder, which means that it arises from a person's immune system...

A new study describes the outcome of corticosteroid use in pregnancy.

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New research led by scientists at Washington State University has found that a protein known as GBP5 appears to play a key role in suppressing inflammation in rheumatoid arthritis, a potentially...

Check out today's top picks from NEJM Group: NEJM Resident 360: Clinical pearls: What are some of the epidemiologic features of atopic dermatitis? What...

A study shows for the first time that long-term infection and chronic inflammation drive CH mediated by the loss of Dnmt3a function. In addition, the study offers key insights into the mechanism by...