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  1. Correct me if Iím wrong but Botox change volume...

    Correct me if Iím wrong but Botox change volume of epidermis?
    So you might end up with no rosacea but with funny shapes of your face.
    A bit like frankenstein. Iím not sure.
  2. Hi Brooks, As far as I remember, I used cromolyn...

    Hi Brooks,
    As far as I remember, I used cromolyn sodium in form of eye drops. Although there was some improvement initially, in the end it was not significant. It did nothing for flushing...
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    It makes sense. But Rhofade is still not...

    It makes sense.
    But Rhofade is still not approved in any country in Europe. And I canít find any application submitted for approval.
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    On the other hand, nobody would want to buy...

    On the other hand, nobody would want to buy useless portfolio?
    Maybe Aclaris is richer and has more expertise in bringing products globally?
  5. Epidermal Overexpression of Xenobiotic Receptor PXR Impairs the Epidermal Barrier and

    http://www.jidonline.org/article/S0022-202X(17)32824-5/fulltext

    I don't know if this was mentioned.
  6. Thanks Ralbihn for great finds. Those are...

    Thanks Ralbihn for great finds. Those are interesting developments. But letís keep in mind that Praxis Biotechnology is a start-up. Hope they will be able to raise enough money to carry on with the...
  7. "Theyíve developed a topical medication targeting...

    "Theyíve developed a topical medication targeting a specific protein that is found in the skin of people with rosacea."
    Interestingly, what kind of protein?
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    I canít find that Allergan filed for Rhofade...

    I canít find that Allergan filed for Rhofade approval in Europe?
    Or would they rather monitor how popular product becomes in US before moving into other markets?
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    EMA website doesn't show Allergan submitted...

    EMA website doesn't show Allergan submitted Rhofade for an approval in Europe.
    It may come with a different name in Europe though.
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    Women have more options to cover up rosacea. But...

    Women have more options to cover up rosacea. But well done. I'm happy for her.
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    Maybe people are using it too often and too thick?

    Maybe people are using it too often and too thick?
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    If Rhofade fails, most likely there won't be...

    If Rhofade fails, most likely there won't be another medication for rosacea in the next 10 years.
    Mirvaso and Rhofade mark this alpha receptor blockers' generation of drugs.
    And if they fail (one...
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    Rhofade as well as Mirvaso are vasoconstrictors....

    Rhofade as well as Mirvaso are vasoconstrictors. Eventually both of them make blood vessels contract.
    Blushing is the outcome of dilated blood vessels. So, in theory those should block blushing too....
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    I didn't find any info that it's meant for...

    I didn't find any info that it's meant for redness or blushing relieve.
    Sun damaged skin is not exactly Rosacea subtype 1.
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    First of all, start taking high doses of vitamin...

    First of all, start taking high doses of vitamin c (500mg-1g) daily.
    High doses of vitamin d3 (2000-10000iu) daily.
    sunscreen free of oil, alcohol. daily.
    try mirvaso. it comes with prescription....
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    Agreed

    Agreed
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    On Rhofade website they offer sample. Apparently...

    On Rhofade website they offer sample. Apparently only in the US.
    Anyone in the US willing to try to obtain it?
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    Iíve read about sides of Rhofade and they look...

    Iíve read about sides of Rhofade and they look very similar to those of Mirvaso.
    The problem with vasoconstrictors, in my view, is that if you use weak formulation, it does little or nothing.
    If...
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    Does anyone know whether they filed for approval...

    Does anyone know whether they filed for approval in Europe?
  20. Mistica, I understand, you experienced rebound...

    Mistica,
    I understand, you experienced rebound flushing. What about the effect straight after it applying?
  21. It appears that lidocaine not only blocks nerves...

    It appears that lidocaine not only blocks nerves but also lowers blood pressure, hence it should affect blood vessels, especially in the area treated.
    The only question, what happens when it stops...
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    Looks a bit bruised after the treatment. Nothing...

    Looks a bit bruised after the treatment. Nothing major.
    Are you planning to have another session? If so, can you do and share your photos just before your second session? So that we could see how...
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    As far as I know coniferous trees soak up...

    As far as I know coniferous trees soak up humidity.
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    You americans are really funny sometimes:))...

    You americans are really funny sometimes:))
    oatmeals!, but who knows, maybe you're right.
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    to me it looks like acne. rosacea is very rare...

    to me it looks like acne.
    rosacea is very rare on forehead.
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