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  1. Rosmarinic acid, Gallic acid, and Caffeic acid study on type-1 Rosacea

    Very interesting and found to have a real therapeutic effect. In some subjects it reduced erythema, in others it held it at baseline. With placebo the rosacea progressed in some patients, it didn't...
  2. If we look at the dysfunction chain that research...

    If we look at the dysfunction chain that research has revealed to now - endoplasmic reticulum stress - the likely treatment vector could very well be topicals, as much as they've failed us in the...
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    Thanks for the considered reply. Do you happen to...

    Thanks for the considered reply. Do you happen to have any info on the penetration depths of the different light wavelengths?
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    Is there any solid evidence of the risk of fat...

    Is there any solid evidence of the risk of fat atrophy and other skin complications from laser? I know I'd like to try laser but that risk / uncertainty makes me reluctant.
  5. You're welcome. I agree, it is very heavy on...

    You're welcome. I agree, it is very heavy on terminology, but the basic takeaway is that "yes, proteins from the B. oleronius bacteria, thought to be resident in Demodex mites, do contribute to...
  6. Activation of Neutrophils Following Exposure to Demodex-Associated Bacterial Proteins

    Kindly provided by one of the researchers (posting here for others to see but will remove at author's request) since it's behind a paywall :



    More evidence that demodex and their resident...
  7. Sure, that's true. Genetic discoveries are useful...

    Sure, that's true. Genetic discoveries are useful because they *might* expose the cause of this disorder at its true origin(s), assuming it is genetic and not something like sun exposure or some...
  8. Tbh, I don't really look forward to waiting till...

    Tbh, I don't really look forward to waiting till a US lab is open (I'm in Europe) and then trying to explain... I hate phone calls and think everything should be done online, but yes I should call. ...
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    Positive in that we're finding out anything new...

    Positive in that we're finding out anything new regarding LL-37, in the long run disabling LL37 would compromise infection-fighting ability of the skin - it's a crucial defense mechanism, even if...
  10. What a shame. If we spent more time on this and...

    What a shame. If we spent more time on this and less on trying random creams we might get somewhere! I e-mailed the labl but they asked me to call, which I can't do.
  11. Genome-wide association study extended (Dr. Anne Chang)

    http://www.rosacea.org/weblog/new-study-discovers-genetic-variants-may-be-linked-rosacea

    That's the link to the original results, but if you look in the Research Grants page, you can see that it...
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    The association to heart health is interesting...

    The association to heart health is interesting but not the main takeaway of the article I think. The interesting part (though details are scarce in the article) for me was the cellular-level...
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    babadah, well the actual final cause isn't yet...

    babadah, well the actual final cause isn't yet known - sorry if I made it sound like that - but what's now coming to light is the downstream physiological mechanism that produces redness =...
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    Hundreds of years ago it was maybe a blessing,...

    Hundreds of years ago it was maybe a blessing, but clearly doesn't apply now. A fine statement for a (likely) non-sufferer scientist to make, not so for us nowink: . At least it elucidates the cause...
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    After reading this when it came out (Dr. Chang's...

    After reading this when it came out (Dr. Chang's work was funded by the National Rosacea Society) I contacted 23andMe to ask if any of their consumer gene services would identify the erroneous SNPs....
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    I agree with you Ariana. Everyone is different...

    I agree with you Ariana. Everyone is different and there are a lot of variations in symptoms displayed.

    I was just reading an article that attempts to "connect the dots" on what we know on Rosacea...
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    As far as medicine goes it's very safe, it would...

    As far as medicine goes it's very safe, it would very likely not make anything worse. Just check that any additives aren't know to irritate skin. Softly softly as usual. And post your findings here...
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    Have you seen a dermatologist? Do that first...

    Have you seen a dermatologist? Do that first before trying anything. Definitely don't go straight for a laser or IPL treatment, those should be thought of as a last resort. First try to get a proper...
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    It's actually quite difficult to be vitamin...

    It's actually quite difficult to be vitamin D-deficient with a modern diet in a first-world country (where most of us are from, I assume). Keep in mind that excess vitamin D can also be a bad thing...
  20. Thread: Capers Cream

    by tica
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    Saw this myself a month or so ago and she...

    Saw this myself a month or so ago and she certainly had a remarkable turnaround. From severe Rosacea to pretty normal looking. I'd give it a try myself but the results seem a bit too good to be true.
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    Hi babadah, I haven't read up on the...

    Hi babadah,

    I haven't read up on the mechanisms of damage caused by steroid (I'm guessing hydrocortisone?) application and only know of the "thins the skin" and steroid addiction concepts. So I...
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    I think the reason we see such a multitude of...

    I think the reason we see such a multitude of suggested causes for Rosacea is that the medical community has only relatively recently had the tools to look at the last few steps of the inflammation...
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    I have what I suspect is Reynauds in my fingers...

    I have what I suspect is Reynauds in my fingers and toes too, when I take Propranolol it doesn't affect it in the slightest, though it does marginally lower my heart rate. Interestingly it completely...
  24. Characterization of Inflammatory Infiltrate in Rosacea Reveals Activation of T-cells

    Had to shorten then title and only an abstract. If anyone with access could attach the full text, it would be appreciated.



    Emphasis mine. Researchers are elucidating more and more of the steps...
  25. Direct links: ...

    Direct links:

    http://blog.hsl.washington.edu/derm/wp-content/uploads/2015/04/rosaceaepi2.pdf
    http://blog.hsl.washington.edu/derm/wp-content/uploads/2015/04/rosaceatx.pdf

    It's on a blog so I'm...
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