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Over the years i have tried lots of antihistamines, even in large doses for months but they have no effect on my redness/flushing. With that I never though a low histamine diet would help.
I decided...

What about topical Isotretinoin (isotrex, Isotrexin), most doctors are more willing to prescribe this as it has less side effects than systemic Isotretinoin.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614089

The above was for acne but it says about Isotretinoin:
"Treatment of patients with isotretinoin significantly decreased monocyte TLR-2...

I have downloaded the full journal and attached it as a pdf to this post. It shows more information and has pictures before/after. (edit - I can't attach the pdf to my post as it's 8MB in size and...

I doubt it will have many reviews yet, It was recently available June 2020 ?
The only short reviews I can find are written in Italian on some Italian pharmacy websites that sell it.

https://onlinelibrary.wiley.com/doi/abs/10.1111/jocd.13707

I believe the full name of the cream mentioned in the medical journal (E-AR) is called 'Eutrosis Ar' Crema and is available on the web...

It would be interesting to find out what doses of Isotretinoin others have taken for Rosacea on this forum when it didn't help them. Search isn't bring up much on doses as low as 2.5mg a day.

I also bough Ketotifen from unitedpharmacies-uk.md way back in 2012. They seem to be based in East Asia / China. Don't know if what I received was genuine or not.
Looking at...

Have the same problem with nose swelling and flushing, main trigger is laying down when sleeping. On this topic, I found a very interesting up to date article about Rhinophyma AND it mentions Vitamin...

I have been reading some posts of Russians with Rosacea (translated) who have had a lot of success using Emoxypine. It is a type of antioxidant and can be bought without a prescription. Has anyone...

When you were reacting to food when it first developed, how long did it take you to stop reacting to food and getting nose flushes. I'm surprised that you say food ceased to have an effect.
Energy...

Never had any anxiety problems or flushing in social situations with Rosacea. Clonidine is working for the flushing I have when going to sleep and food related flushing. It stops the swelling I...

I started taking Clonidine 4 weeks ago, only 1 tablet a day - 25mcg at night - about 1hr before I go to bed. This is to stop flushing that happens at night. It is working very well right from the...

I tried this MSM, bought the powder version as it was cheaper(250g tub) same stuff as inside the capsules and comes with a little plastic scoop that measures 1000mg. I find that when it controls the...

Pretty interesting medical journal published in Italy about treating Rosacea by putting Rose petals on face and bringing about remission after 1 week.

...

Searching pubmed there is an interesting article about topical antihistamines. Diphenhydramine was one of the ones used.
"TOPICAL ANTIHISTAMINES DISPLAY POTENT ANTI-INFLAMMATORY ACTIVITY LINKED IN...

Similar symptoms. You can tell when it is swelling just from the sensation. About the yogurt masks, do you just use natural yogurt with nothing else and leave it on your nose all night.
The nose...

In the UK you can do an online consultation via a number of pharmacies (always check the pharmacy first via https://medicine-seller-register.mhra.gov.uk ). It involves answering a series of...

Nose swelling is common. You don't mention what type of Rosacea you have, flushing or p&p. Usually heavy flushing can cause nose swelling that then goes away after a few hours. Is it red and swollen...

Quote Originally Posted by RedRecluse View Post
Did you order your ZZ cream directly from Demodex Solutions?
I got mine from Demodex.co.uk



Is Demodex.co.uk a legit site for ZZ cream. It's...

From reading past posts I thought this only worked for type 2 papules/pustules and is very drying. Did It actually stop your flushing when laying down. How long did it take to work.

Looking at past posts of people who flush when they go to sleep it might be linked simply to posture. You can rule it out by lying down on a couch for 20 minutes during the day. If you have a flush...

Any updates Geoff, is it working for the flushing when laying down? What dose are you on.

Which one did you take? I tried Amitriptyline 20mg in 2015 for 6 weeks. It took 5 weeks before it helped at reducing flushing and tingling pain. In the 6th week because of side effects, mainly...

https://onlinelibrary.wiley.com/doi/abs/10.1111/exd.13881

Personalized medicine to treat Rosacea at the genetic level. Also interesting that many genes linked to all Rosacea variants (unlike acne)...