Swollen nose every morning

[YankeesRtheBest Senior Member Find all posts View Profile Close YankeesRtheBest]

My swollen nose seems to be the most apparent when I wake up in the morning and I was curious if anyone has this problem too. It also seems to be swollen at other times of teh day. Dr. Nase mentioned the therapies below that we all have to be cautious with. The one in letter G, Oral Metronidazole 250 mgs 3 times per day, seems to be the best choice for me because I honestly don't have much more money for any kind of treatment and I can get covered by insurance for meds, but I'm not sure how wise it is to take this in the stage I'm in. What do you think Dr. Nase? I just want to know that I'm doing my BEST to address my nose now because it's continuing to swell more as time goes by. I'm not doing one single thing to address this. Thanks. -Chris



1. Skin swelling/isolated raised patches of swelling or mild fibrosis:

a. The epidermis does not contain any blood vessels (arterioles, venules or lymphatics) and swelling occurs below the epiidermis at the top layer of teh dermaol tissue. Thus the micropeel would have no effect as it just treats 20% to 70% of the epidermal skin.

b. Very mixed results with levulan followed by IPL, Sciton, or V-beam.

c. Stay away from freezing which is still performed

d. Oral isotretinoin + Oral Ketotifen seem to be the best.

e. I have heard of experiments with local injection of BOTOX, Ketotifen + Roxithromycin, Weekly shots of Retinol deep into the fibroblasts.

f. ketotifen 1-2mg /day in combination with isotretinoin 0.2-0.5mg/kg/day for 4-5 months. Reported to work in Morbihan's disease.

g. Hydroxychloroquine 200mg twice daily (antimaliarials under tight medical supervision actually help many rosacea symptoms)

h. Furosemide, a potent diuretic has been used in some cases under very tight medical supervision

g. Oral Metronidazole 250 mgs 3 times per day for no longer than 28 days (under very tight medical supervision). This treatment can be a real God-send to lymphedema and rhinophyma sufferers ........ as well as those caught in a very bad case of rosacea inflammation.

[Mknlvi Member Find all posts View Profile Close Mknlvi]

I have the exact same problem, suffered with it for years. In my case something is happening when I sleep, which always makes my nose swollen by the time I wake up in the morning. It is not really red at all, but always swollen.

I was prescribed Flagyl (Oral Metronidazole) last year. I was put on one 500mg and one 250mg per day.
The results were poor. It didn't help at all for the 12 days while I was taking it, but the week after my nose was less swollen for around 2 weeks. The swelling then came back just as bad as before I took it.

[lakan Senior Member Find all posts View Profile Close lakan]

I have the same problem, swollen nose in the morning. But what seems to help me is the medication Klacid (clarithromycin). It has got a lot better since i've started eating that. Don't know why it helps though..but it does. I take 250mg in the morning and 250 in the evening.

[YankeesRtheBest Senior Member Find all posts View Profile Close YankeesRtheBest]

Thanks for the info, I have high hopes for Rambazole, Dr. Nase said it can treat mild to moderate rhinophyma. I just hope that mine will stay in or below that range when it comes out. And I wonder if that means it will prevent me from ever getting to a severe stage? I sure hope so. Until then, I'm looking for the best way to stop this swelling and other symptoms of rhinophyma in its tracks. I'm still unsure about what the best laser is for this. Maybe that Roche place in NJ can make the 1 mg accutane if I get my derm to send the prescription. -Chris

[isitrosacea Senior Member Find all posts View Profile Close isitrosacea]

I have the same thing, my nose is swollen in the morning for an hour or so. And another thing is that my nose always gets stuffed during nights... that probably causes the swelling too. It's very damn irritating, please let me know if anything has helped you guys.

[Melissa W Moderator Find all posts View Profile Close Melissa W]

Could be partly due to allergies.
Have you tried an antihistamine like allegra or zyrtec?

Best wishes,
Melissa

[isitrosacea Senior Member Find all posts View Profile Close isitrosacea]

Could be partly due to allergies.
Have you tried an antihistamine like allegra or zyrtec?

Best wishes,
Melissa

I don't have any allergies that I know of. But yeah, I could have some allergy that I don't know of since I got the fungus and seb. derm and all. Dunno if those conditions are related in any way, though.

[phlika29 Moderator Find all posts View Profile Close phlika29]

Do you sleep on a feather pillow. You might like to put an allergy slip cover on it.

[isitrosacea Senior Member Find all posts View Profile Close isitrosacea]

Do you sleep on a feather pillow. You might like to put an allergy slip cover on it.

Yeah I do... I'm gonna test sleeping without a pillow for the next night.

[phlika29 Moderator Find all posts View Profile Close phlika29]

Well that sounds a little uncomfortable. You can buy special covers for pillows and buy special hypoallergenic ones. Ofcourse it might not be that....

[isitrosacea Senior Member Find all posts View Profile Close isitrosacea]

Well that sounds a little uncomfortable. You can buy special covers for pillows and buy special hypoallergenic ones. Ofcourse it might not be that....

Yeah I didn't actually try sleeping without a pillow... but my nose got way stuffed again. It could be the excessive heating, it's like -13 in the outside now so the heaters are boiling.

[Melissa W Moderator Find all posts View Profile Close Melissa W]

We keep the heat off in the bedroom. That could be an aggravating factor.

Best wishes,
Melissa

[Stefieny Junior Member Find all posts View Profile Close Stefieny]

Hi Chris,

I found your posting while searching online for information on Rhinophyma and swollen nose. I was recently diagnose with Rosacea and already experiencing your symptoms. My nose is slightly larger than before and it tends to be more swollen when I wake up in the morning. I am horrified since I am a female in my early 30's. I was curious if you tried any medication that improve your condition. I am currently using Metrogel, but its not helping at all. If anyone else is experiencing the same problem and has good advice, please feel free to drop a note.

Thanks!!!

[Melissa W Moderator Find all posts View Profile Close Melissa W]

Hi Stefieny,
I'm sorry you are dealing with this. You might find this thread helpful.
It contains helpful threads within it as well dealing with this issue.

http://www.rosaceagroup.org/The_Rosa...ght=rhinophyma


There are measures you can take so don't stress too much. Best thing to do is find a good derm who can work with you to help you find relief from your symptoms.

Welcome to the RF


Best wishes,
Melissa

[RedFaced Senior Member Find all posts View Profile Close RedFaced]

I am also dealing with nose swelling and I know it can another distressing part of Rosacea.

I have done some reseach on it and here is some advice.

It has been studied and proven through biopsy that Rhinophyma and Rosacea have an overgrowth of mast cells. Mast cells play a role in the release of histamine, thus too many mast cells, too much histamine, too much histamine leads to inflammation, prolonged inflammation leads to swelling, prolonged swelling can lead to fibrosis and tissue growth. So goes the basic theory for phymatous types of Rosacea.

On top of that, Sebum and the overactive activity thereof is also said to play a role in Rhinophyma. This is one reason why it is said to be more prevelant in men then women, as androgens influence the oil glands and sebum.

This is why Dr. Nase encourages Oral Ketofin (sp?) and low dose Accutane as it covers both of these issues and on top of that, Accutane has potent anti-inflammatory effects.
However, I caution you on low dose Accutane. I did it for 8 months. It helped the nose a lot, actually reversed the swelling I had BUT it ended up making my overall facial flushing worse and once I was off for around 6 mopnths the nose swelling came back. I would only entertain this medication IF you have exhausted all other avenues and I would also go very slow and not go above 10-15mg per day, keeping a close eye on flushing.

Quercetin/Bromelian. This is a natural supplement that has anti-inflammatory effects, strengthens cappillaries and is a mast cell stabilizer. I have found it too be somewhat beneficial but in no means a cure. Has perhaps just allowed things to be less severe? I hope anyways.

Chromolyn Nose Spray. This is an OTC nose spray that is also a mast cell stabilizer. I do 3 squirts per day. Can't say how much it has really hepled, but I think it has again perhaps made things less severe. Nonethelss, I use it daily in hopes that it is helping to make things less severe. Some people respond well to this, so I have read.

Clonidine. Didn't help me but I have read reports of people having resolved nose flushing with this.

Like most aspects of Rosaea, the key to control is reducing the flushes, which reduces the overall inflammation, which reduces the swelling, wich limits or prevents the possibility of tissue growth.

Mast cells/Fibrosis and their role in Phymatous types of Rosaca as well as Rosacea in general.

http://www.find-health-articles.com/...rhinophyma.htm
http://rosacea-support.org/angiogene...volvement.html
http://www.springerlink.com/content/8mh5517688160212/
[ame="http://www.youtube.com/watch?v=eVBqMXMIFnM"]YouTube - Mast Cell[/ame]

Histopathology Skin nose--Rhinophyma on Sebacous Glands

[ame="http://www.youtube.com/watch?v=CqpaU4SU2Dk"]YouTube - Histopathology Skin nose--Rhinophyma[/ame]