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Medical Study Paper: SIBO highly correlated to Rosacea Sub Type 2 (demodex)

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  • Medical Study Paper: SIBO highly correlated to Rosacea Sub Type 2 (demodex)

    SIBO medical study concluded with "SIBO seems to play a role in triggering rosacea, especially Subtype II (rosacea with papules and pustules). Subtype II skin damage is highly correlated to demodex skin mites.

    In this small study with a 3 year followup, SIBO was found in 1 patient with Subtype 1 rosacea (98.3%) and 19 patients (52.8%) with Subtype 2 Rosacea.

    Patients were treated with Rifamaxin with follow ups for 3 years. They found that treatment of SIBO determine clinical remission in all patients. The remission persisted in the majority of patients during the follow up period. The authors noted that remarkable treatment success finding as frequent rosacea relapses are often observed with traditional therapies. In other words, don't treat the symptoms, find and treat the real cause!

    Note: Rifaximin, is an antibiotic that is highly effective against some types of bacteria E coli, Salmonella and Shigella bacteria. Rifaximin is poorly absorbed, so it is not expected to have any impact on bacteria anywhere else in the body including the skin. Rifaximin while highly effective against E Coli, is also extremely expensive. Rifaximin also isn't touted as being effective against other types of bacteria that are also associated with SIBO including Bacteriodes and Eggerthella Lenta. Other antibiotics, like Oral Metronidazole (Flagyll), are highly effective against Bacteriodes and Eggerthella Lenta. It is important to get the right antibiotic(s) to be effective against the specific bacteria causing the SIBO. If multiple types of bacteria are causing skin issues, it may take more than one antibiotic to clear the bacterial overgrowth. A good diagnostic test for specific strains of bacterial overgrowth is necessary for a successful treatment.

    The bacterial overgrowth may be either inhibiting the immune system from working properly to keep the demodex skin mites under control OR it may be producing chemicals that allow the demodex to flourish on the skin and become overpopulated.

    https://www.jaad.org/article/S0190-9622(16)30014-7/pdf
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