Mirvaso user experience

[metalgear85]

The other Mirvaso thread is getting very long, with only a few posts from actual users.

I put Mirvaso on yesterday at about 10 am. I used about a pea-sized amount on my cheeks and nose. It absorbs into the skin very well, almost too well. You have to spread it quickly to make sure you dont get too much on only one small portion of your face. It does also seem to moisturize a bit as previously mentioned on the Rosacea blog I believe - my skin never felt dry with it on. I only have redness and flushing on the center of my face - not on the sides of my face, like by my sideburns.

I looked in the mirror 30 min later, and saw a very minimal improvement in the redness. I looked again about 2 hours later, and the redness had dramatically improved. I could only see a slight shade of red on my cheeks and nose. Maybe if I used more my face would be totally white, but I'm going to stick with using a minimal amount. It looked a lot like it does the few days after I have a vbeam. The redness is way down, but not completely gone. Unfortunately, with vbeam the redness gradually comes back within a few days. There were 2 moments yesterday that would normally cause a flush for me, but when I looked in the mirror I didnt see any additional redness. I did feel a hotness in my face due to what felt like a flush, but no other symptoms of a flush.

When I woke up this morning (about 8 am), I did notice my cheeks look slightly more pink that they usually do. I'm sure my cheeks have looked this way at some points over the previous years, so it doesnt worry me. It's only slightly noticeable. Curiously, my nose looks a bit less red than it normally does.

I'm skeptical that Mirvaso will work this well indefinitely, but I will keep using it daily - only a minimal amount like I described.

[poppe]

If tests are to be credible, should also post pictures (before and after) their own face.

[anon24]

So the first time I tried it, I applied a pea size amount on my checks, chin, nose, and forehead as the directions say. My face was great for 24 hours, but it took 3 days for it to call down, and I had flushing and redness in weird places that I never do, and I never had flushing before. I am now trying a pea size amount for the entire face to see if I have less side effects, and will report back. I am also going to apply every day for a few days and then stop for a few days and see what happens

[Acanthous]

I'm not sure how many people will see this review here, but the FDA approval thread is crazy long and full of cruft so hopefully people will find this thread. My report:

I used 3 pea-sized blobs for whole face, at 2pm on the day I got the script ($50 w/coupon). I am a flusher, with many, many triggers, including 'being alive' and 'breathing'. Deepest flushing is on nose and cheeks, but rest of face, neck and chest also flush. I always have some redness. Observations:

- I was white like a vampire for approximately 14-15 hrs. Not even red wine and pasta made the treated areas flush.
-this is not as good a look as I imagined it would be. Also, it highlighted the neck and chest flushing I have.
- some normal flushing started coming back on face and cheeks around 8am the next day.
- extreme, weird rebound flushing on cheeks starting by 9 am. Deep, blotchy flush, very hot and uncomfortable. I was actually able to get in for an IPL treatment, reasoning that it might be a good time to target the most disordered capillaries. I had more swelling than usual from the IPL. Hopefully it zapped some stuff good.
- oddly, my nose stayed quite pale much longer than the rest of my face and did not seem to rebound badly.
-3 days post-mirvaso and 2 days post-ipl, flushing is low on most of my face, but one cheek became very flushy and warm around 9:30 after my habitual morning green tea. It's still disproportionally flushed but better.

I will probaby spot-test mirvaso again, using a tiny fraction of the prescribed amount. But my initial experience suggests that, for me, great caution is warranted.

Good luck everyone.

[red11]

I'm not sure how many people will see this review here, but the FDA approval thread is crazy long and full of cruft so hopefully people will find this thread. My report:

I used 3 pea-sized blobs for whole face, at 2pm on the day I got the script ($50 w/coupon). I am a flusher, with many, many triggers, including 'being alive' and 'breathing'. Deepest flushing is on nose and cheeks, but rest of face, neck and chest also flush. I always have some redness. Observations:

- I was white like a vampire for approximately 14-15 hrs. Not even red wine and pasta made the treated areas flush.
-this is not as good a look as I imagined it would be. Also, it highlighted the neck and chest flushing I have.
- some normal flushing started coming back on face and cheeks around 8am the next day.
- extreme, weird rebound flushing on cheeks starting by 9 am. Deep, blotchy flush, very hot and uncomfortable. I was actually able to get in for an IPL treatment, reasoning that it might be a good time to target the most disordered capillaries. I had more swelling than usual from the IPL. Hopefully it zapped some stuff good.
- oddly, my nose stayed quite pale much longer than the rest of my face and did not seem to rebound badly.
-3 days post-mirvaso and 2 days post-ipl, flushing is low on most of my face, but one cheek became very flushy and warm around 9:30 after my habitual morning green tea. It's still disproportionally flushed but better.

I will probaby spot-test mirvaso again, using a tiny fraction of the prescribed amount. But my initial experience suggests that, for me, great caution is warranted.

Good luck everyone.

Don't suppose you have tried applying mirvaso when you have the rebound flushing?

[Acanthous]

Don't suppose you have tried applying mirvaso when you have the rebound flushing?

I didn't dare. The rebound flush was much worse than my usual, and I flush a lot normally. The skin was nearly purple in spots. I just felt the outcome was too unpredictable.

[wjs]

Rebound redness

I didn't dare. The rebound flush was much worse than my usual, and I flush a lot normally. The skin was nearly purple in spots. I just felt the outcome was too unpredictable.

Hi,

I have found that applying 0.5% or 1% hydrocortisone cream (over the counter) 4-6 hours after Mirvaso greatly reduces any rebound redness and eases the transition as the Mirvaso wears off. I have consulted with many dermatologist friends who agree that this is not hazardous. OTC 0.5-1.0% hydrocortisone is very mild, is not a fluorinated steroid and does not pose a long-term risk. Give it a try. It works.

[metalgear85]

Update

Like another person has said, when I wake up in the morning my nose looks less red than it normally does. I'm not sure if Mirvaso has some sort of long term affect.
My cheeks havent looked extra pink in the last couple of days, like they did the first morning after using Mirvaso.

It takes 1-2 hours for Mirvaso to reach it's full force for me. It lasts about 8 hours after that (in my case). So, if I put it on at 0700, and I work until about 1700 or 1800, Mirvaso may start to wear off late in my work day. Maybe it's because I use such a minimal amount of Mirvaso - it may not last the 12+ hours advertised.

I have had a couple of flushes since using Mirvaso. I dont consider it rebound flushing, but it seems Mirvaso will just mitigate, not completely prevent flushing for me. Overall, my flushing seems to be less frequent while using Mirvaso.

I do occasionally get a crazy stare when I'm in public with Mirvaso on. Another user pointed out Mirvaso can make your skin look sort of odd, or unnatural (?). Maybe because of how white Mirvaso generally makes my cheeks and nose look? It may also be related to the black and blue dark coloration around my eyes that I've always had. I'm going to research what to do about dark circles around my eyes. Regardless, I like Mirvaso and will continue to use it daily.

[wjs]

Like another person has said, when I wake up in the morning my nose looks less red than it normally does. I'm not sure if Mirvaso has some sort of long term affect.
My cheeks havent looked extra pink in the last couple of days, like they did the first morning after using Mirvaso.

It takes 1-2 hours for Mirvaso to reach it's full force for me. It lasts about 8 hours after that (in my case). So, if I put it on at 0700, and I work until about 1700 or 1800, Mirvaso may start to wear off late in my work day. Maybe it's because I use such a minimal amount of Mirvaso - it may not last the 12+ hours advertised.

I have had a couple of flushes since using Mirvaso. I dont consider it rebound flushing, but it seems Mirvaso will just mitigate, not completely prevent flushing for me. Overall, my flushing seems to be less frequent while using Mirvaso.

I do occasionally get a crazy stare when I'm in public with Mirvaso on. Another user pointed out Mirvaso can make your skin look sort of odd, or unnatural (?). Maybe because of how white Mirvaso generally makes my cheeks and nose look? It may also be related to the black and blue dark coloration around my eyes that I've always had. I'm going to research what to do about dark circles around my eyes. Regardless, I like Mirvaso and will continue to use it daily.

I definitely agree!

[anon24]

Metalgear,

How much are you using, and when you don't wear it, does the redness start to come back in weird patterns? aand is the redness exagerrated at first when it starts coming back, adn then calms down after a couple days? That's what has happened with me..

[hihohi88]

Like another person has said, when I wake up in the morning my nose looks less red than it normally does. I'm not sure if Mirvaso has some sort of long term affect.
My cheeks havent looked extra pink in the last couple of days, like they did the first morning after using Mirvaso.

It takes 1-2 hours for Mirvaso to reach it's full force for me. It lasts about 8 hours after that (in my case). So, if I put it on at 0700, and I work until about 1700 or 1800, Mirvaso may start to wear off late in my work day. Maybe it's because I use such a minimal amount of Mirvaso - it may not last the 12+ hours advertised.

I have had a couple of flushes since using Mirvaso. I dont consider it rebound flushing, but it seems Mirvaso will just mitigate, not completely prevent flushing for me. Overall, my flushing seems to be less frequent while using Mirvaso.

I do occasionally get a crazy stare when I'm in public with Mirvaso on. Another user pointed out Mirvaso can make your skin look sort of odd, or unnatural (?). Maybe because of how white Mirvaso generally makes my cheeks and nose look? It may also be related to the black and blue dark coloration around my eyes that I've always had. I'm going to research what to do about dark circles around my eyes. Regardless, I like Mirvaso and will continue to use it daily.

Be pale, the dream *-*

You think a tube of Mirvaso (if you use Mirvaso daily with enough product for deleted all redness and be pale) can last how long ? Change of tube every month ? Because 50€ every month for a normal skin, ouch ..

[Starlite]

Hi,

I have found that applying 0.5% or 1% hydrocortisone cream (over the counter) 4-6 hours after Mirvaso greatly reduces any rebound redness and eases the transition as the Mirvaso wears off. I have consulted with many dermatologist friends who agree that this is not hazardous. OTC 0.5-1.0% hydrocortisone is very mild, is not a fluorinated steroid and does not pose a long-term risk. Give it a try. It works.

From this thread... Mirvaso has been approved by the FDA. Post #473

<snip>. Wjs was the same who repeatedly advised people here to just add hydrocortisone to the mix in order to prevent rebound flushing, which is really an almost outrageous thing to advice people here given the contraindication of steroids-cortisone and rosacea skin. <snip>

"Many dermatologist friends?" Really? Please don't advise people to mix two medications that no one knows their interactions and possibly mask a reaction that may be causing damage unseen until it is too late. The board has many stories of people who have had years of trouble after using steroids and/or hydrocortisone on the advice of "dermatologist" or by personal choice. Do a forum search for yourself. Don't take my word for it. They report thinned skin, overgrowth of a fungus that bloomed after discontinued use, and worsening of their rosacea symptoms.

If that is what you are doing, you are risking long term damage to your skin. Think about it, if the Mirvaso is causing you to rebound and you are masking that with OTC 0.5-1.0% hydrocortisone, you are taking away your ability to see this medication is not right for you and listen to the warnings to stop using it. Nat reports that it took a while for her body to recover and stop flushing badly after her test of brimonidine, the active ingredient in Mirvaso.

[Mirvaso2013]

From this thread... Mirvaso has been approved by the FDA. Post #473


"Many dermatologist friends?" Really? Please don't advise people to mix two medications that no one knows their interactions and possibly mask a reaction that may be causing damage unseen until it is too late. The board has many stories of people who have had years of trouble after using steroids and/or hydrocortisone on the advice of "dermatologist" or by personal choice. Do a forum search for yourself. Don't take my word for it. They report thinned skin, overgrowth of a fungus that bloomed after discontinued use, and worsening of their rosacea symptoms.

If that is what you are doing, you are risking long term damage to your skin. Think about it, if the Mirvaso is causing you to rebound and you are masking that with OTC 0.5-1.0% hydrocortisone, you are taking away your ability to see this medication is not right for you and listen to the warnings to stop using it. Nat reports that it took a while for her body to recover and stop flushing badly after her test of brimonidine, the active ingredient in Mirvaso.

You cant argue with any of that

[wjs]

You cant argue with any of that

Actually, I found that OTC 2% diphenhydramine (Benedryl) cream applied 4-6 hours after Mirvaso works as well as topical 1% hydrocortisone. I have absolutely no rebound and my face gradually transitions back to its normal state.

This will be my last post here. You guys are really way too hostile.
Best of luck to all of you.

[Littlelassie]

I used Mirvaso for three days. The first day I used too much (still less than the recommended amount). I was very pale and it looked abnormal, and lasted for 6-8 hours. The second two days I used less and started to see signs of rebound when it would wear off. Honestly I didn't believe in a "rebound", I'm not sure why. I especially didn't think I would be someone that had a rebound. A day after I stopped the mirvaso, I flushed really badly. That was the first time I've ever really flushed. It has been 5 days since I've used any mirvaso and I still have been getting flushy/extra red when I get too warm or eat something spicy. Those are normal triggers for people who typically flush, but I didn't flush before this. I'm hoping that if I'm gentle on my skin and avoid getting too warm things will settle out and go back to how there were before. My advice is just to be careful. Take it slow and don't use too much. Hopefully a lot of people can still benefit from this, but I'm too scared to try it again. If I get a good baseline picture (when my skin is looking normal) I will post some pics. I have some with the mirvaso on and 1 during the flush (my husband was impressed with the redness and felt the need to document).