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Mepacrine/Quinacrine cured my flushing but still red/ruddy

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  • Mepacrine/Quinacrine cured my flushing but still red/ruddy

    Like others on the board I've had success with Quinacrine to get the flushing under control. I honest to god haven't flushed in almost 4 months. Last year I had the same routine with work and I was in full on intense flush by 2pm daily. Its been a lot hotter than it was last year too.

    What it hasn't helped though is the baseline redness/ruddiness and I'm kind of at a loss with what I should do about it. I do get some sun throughout the day, but lot for long periods. I also wear sunscreen everyday.. Would that prevent my complexion from getting better?

    Have any of you that have used a anti-malarial or something that stopped flushing seen an improvment in your complexion over time?
    Last edited by Ray; 8 August 2011, 02:16 AM.

  • #2
    Hey how are you? Sorry i actually dont know the answer to your question as i have never used an anti-milarial. But i am curious, how did you get prescribed Mepacrine just for flushing? Or do you have other auto-immune symptoms aswell?

    Thanks.

    Comment


    • #3
      Hello Ray, Although I have no experience with the antimalarial drugs.. I am wondering if your complexion is Red and Ruddy due to Broken capillaries under the skin? This is my problem, I have pretty much got rid of the redness however the visible veins make me look very Ruddy and those are the only parts of my face that get red throughout the day as well.

      Comment


      • #4
        Originally posted by pleasehelp123 View Post
        Hey how are you? Sorry i actually dont know the answer to your question as i have never used an anti-milarial. But i am curious, how did you get prescribed Mepacrine just for flushing? Or do you have other auto-immune symptoms aswell?

        Thanks.
        Yup, my derm prescribed it just for flushing. She almost couldn't get her presciption notepad out fast enough.. Maybe cause she's sick of me.. Who knows! She knows I have a severe case though and I've seen her probably a dozen times over a 3-4 year period about it.

        I had Accutane induced flushing by way, which may or may not respond better to anti-malarials.

        Comment


        • #5
          Originally posted by amethystice215 View Post
          Hello Ray, Although I have no experience with the antimalarial drugs.. I am wondering if your complexion is Red and Ruddy due to Broken capillaries under the skin? This is my problem, I have pretty much got rid of the redness however the visible veins make me look very Ruddy and those are the only parts of my face that get red throughout the day as well.
          It probably is the broken caps from all the flushing etc over four years. Is that what diffuse redness is? I think sun exposure and constantly being out in the heat might be playing a role of it not getting any better. I'm going to school in the fall and my routine will be a little more rosacea friendly, so maybe that'll help. How did you go about getting rid of the redness?

          Comment


          • #6
            The flushing went away after I started using Ivermectin topically and orally and HP and borax solution on the days/nights I don't use ivermectin. Like I said I still have the redness but only where I can see the broken capillaries, mine are very visible. And for the past two years I WAS out in the sun all summer long and it is also very hot here. People would always ask me if I wanted sunscreen because my face was always red, I didn't have the broken capillaries though until I had a bad reaction to some make up at the end of march, this year. my face was tomato red and bumpy after this bad reaction (i had no bumps previous to this reaction) for about a week, then after that BAM.. broken caps everywhere, I think If I could get rid of them I wouldn't have any redness other than what normal people have. I am currently getting IPL done as well, I have had two VBEAM lasers but they didn't help so I just started doing the IPL ,last week was my first one, then I have another next week.

            Comment


            • #7
              Hi

              If you really want to make a dent in getting rid of base redness without oral medication you really need to invest in IPL or Vbeam treatments. I haven't had IPL myself, but i've had vbeams and they've done wonders. Redness is due to the dilated or inflammed blood vessels, so the vbeam is great at zapping/absorbing them.. that's why people see more results as they continue with regular treatments. It would be a good idea to seek advice from a specialist laser Derm if you are interested in either treatments.

              Best, shantelle
              Shantelle

              31 Year old female from NZ

              Comment


              • #8
                Originally posted by shantelle View Post
                Hi

                If you really want to make a dent in getting rid of base redness without oral medication you really need to invest in IPL or Vbeam treatments. I haven't had IPL myself, but i've had vbeams and they've done wonders. Redness is due to the dilated or inflammed blood vessels, so the vbeam is great at zapping/absorbing them.. that's why people see more results as they continue with regular treatments. It would be a good idea to seek advice from a specialist laser Derm if you are interested in either treatments.

                Best, shantelle
                Hey Shantelle, I've obviously thought about doing IPL or Vbeam, but for me its been a commitment thing. I read so much stuff on here about fat loss and whatever that I guess I'm just trying to exhaust all my options before commiting. I will though.. Its just how it has to be. I got the flushing under control which is sweet, so that should really help with losing the diffuse redness. My derm's clinic doesn't have a vbeam though, just a lumenis one IPL. Its a professional clinic though and I do somewhat trust them..

                What do you think of the demodex treatment with BP and borax? Probably won't do a thing for those that developed rosacea from the A eh?

                Comment


                • #9
                  Ahh yes 'Ray', same as myself. Finished accutane 9 months ago, started a topical retinoid to keep it under control. Been flushing for the past 6 months. Been off all meds for 4 months, things continue to get worse.

                  Everyone who seems to go on an anti-milarial such as Mepacrine or Planequil have had their flushing stop. I do wonder if my derm would prescribe me it. Although im planning on trying another med first such as Clonidine or Remeron if i can.

                  What side effects have you had from Mepacrine? Is the yellowing of the skin bad?

                  Comment


                  • #10
                    Originally posted by pleasehelp123 View Post
                    Ahh yes 'Ray', same as myself. Finished accutane 9 months ago, started a topical retinoid to keep it under control. Been flushing for the past 6 months. Been off all meds for 4 months, things continue to get worse.

                    Everyone who seems to go on an anti-milarial such as Mepacrine or Planequil have had their flushing stop. I do wonder if my derm would prescribe me it. Although im planning on trying another med first such as Clonidine or Remeron if i can.

                    What side effects have you had from Mepacrine? Is the yellowing of the skin bad?
                    I did get a bit of yellowing, but its really not noticeable. It kind of just blends in with tanned skin. Doesn't bother me at all.

                    Comment


                    • #11
                      Originally posted by pleasehelp123 View Post
                      Everyone who seems to go on an anti-milarial such as Mepacrine or Planequil have had their flushing stop. I do wonder if my derm would prescribe me it.
                      I take hydroxychloroquine (plaquenil) for connective tissue disease, I have to say it has had no effect on my terrible flushing at all, even when I increased the dose to 400mg a day.

                      Comment


                      • #12
                        Originally posted by y-gwair View Post
                        I take hydroxychloroquine (plaquenil) for connective tissue disease, I have to say it has had no effect on my terrible flushing at all, even when I increased the dose to 400mg a day.
                        I'm very sorry to hear that. Maybe your doctor and you would consider trying Mepacrine/Quinacrine or another anti-flush med. For the sake of anecdotal data, could you tell us if you have ever taken Accutane? Anti-malarials seem to work very well for those that develop flushing while taking Accutane. Thats the theory anyway.

                        Comment


                        • #13
                          Originally posted by shantelle View Post
                          Hi

                          If you really want to make a dent in getting rid of base redness without oral medication you really need to invest in IPL or Vbeam treatments. I haven't had IPL myself, but i've had vbeams and they've done wonders. Redness is due to the dilated or inflammed blood vessels, so the vbeam is great at zapping/absorbing them.. that's why people see more results as they continue with regular treatments. It would be a good idea to seek advice from a specialist laser Derm if you are interested in either treatments.

                          Best, shantelle
                          I forgot to ask Shantelle, did you see any improvment in your diffuse redness etc after your anti-malarial kicked in and your flushing went away? For some people it did, didn't it? I'm still holding on to that hope before going for the IPL I guess..

                          Comment


                          • #14
                            Originally posted by Ray View Post
                            I forgot to ask Shantelle, did you see any improvment in your diffuse redness etc after your anti-malarial kicked in and your flushing went away? For some people it did, didn't it? I'm still holding on to that hope before going for the IPL I guess..
                            Yes, maybe about 25%. It helped more with he flushing/burning for me though. Vbeam has really helped my base redness; nothing else has had as much impact as that has.
                            Shantelle

                            31 Year old female from NZ

                            Comment


                            • #15
                              Originally posted by Ray View Post
                              I'm very sorry to hear that. Maybe your doctor and you would consider trying Mepacrine/Quinacrine or another anti-flush med. For the sake of anecdotal data, could you tell us if you have ever taken Accutane? Anti-malarials seem to work very well for those that develop flushing while taking Accutane. Thats the theory anyway.
                              I had no expectation that it would, it came as a surprise that it was used for rosacea. My GP was convinced it was causing the flushing and suggested I should stop, yet another misguided diagnosis!

                              No Accutane, I was taking hydroxychloroquine for about 9 months before the flushing started too. We're fairly sure the flushing/burning is steroid induced (steroid eye drops).

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