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Innate type 2 immunity controls hair follicle commensalism by Demodex mites

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  • operationStone
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    Where can I read more? Your link is not valid anymore..

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  • SpringerHeather
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    I would never have thought that there could be hair mites in our body. I thought they appear only in case of infection with hair parasites. When I wore dreadlocks for a long time, due to lack of hygiene, I got parasites. It's quite strange that my husband also wears black men braids, but he's fine and has never had any problems.​

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  • Innate type 2 immunity controls hair follicle commensalism by Demodex mites

    Demodex mites are commensal parasites of hair follicles (HFs). Normally asymptomatic, inflammatory outgrowth of mites can accompany malnutrition, immune dysfunction, and aging, but mechanisms restricting Demodex outgrowth are not defined. Here, we show that control of mite HF colonization in mice required group 2 innate lymphoid cells (ILC2s), interleukin-13 (IL-13), and its receptor, IL-4Ra-IL-13Ra1. HF-associated ILC2s elaborated IL-13 that attenuated HFs and epithelial proliferation at anagen...

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