Mirvaso has been approved by the FDA.

[Vovin]

Apparently Canadians can now buy Mirvaso?

http://www.canadapharmacyonline.com/DrugInfo.aspx?name=Mirvaso6982

You need to fax a prescription but you could just go see your family doctor and have him write it. I don't know how this is possible since it's not officially released in Canada but they are a credited pharmacy.

[red11]

red 11, did you test mirvaso yet ? can you tell us more about your experience ? how does it work for you, rebound flushing etc... ?

It works ok not as good as I thought! My cheeks still stay red not as bad as normal they are usually extreamly red anyway, defo get a bit of rebound flushing but flushing is the worst part for me anyway so it's hard to judge if its much worse or not. I would not pay full wack for mirvaso but being on prescription isn't quite as bad on the wallet.

[Brady Barrows]

It works ok not as good as I thought! My cheeks still stay red not as bad as normal they are usually extreamly red anyway, defo get a bit of rebound flushing but flushing is the worst part for me anyway so it's hard to judge if its much worse or not. I would not pay full wack for mirvaso but being on prescription isn't quite as bad on the wallet.

Can't conclude from your statement above whether to count your experience as positive or negative, so I have put you with the ambiguous reports in Post #15. If you ever decide one way or the other, let us know. I would say if you are continuing to use Mirvaso for a month or more and you have decided to continue using it, maybe your report should be in the positive reports. Keep us informed.

[Brady Barrows]

How about this report?

"I am a physician and have prescribed Mirvaso for many of my patients. No significant problums thus far." Dr W, 45-54 Female on Treatment for 6 months to less than 1 year (Caregiver) 5/1/2014 11:43:28 AM

[Aldous]

My experience with Mirvaso

Hello there

I recently bought Mirvaso from 'pharmacy2u' in the UK. I've been using it for about a week now. About an hour after first use I noticed the redness had gone completely - in fact I looked slightly pale. Wonder drug, I thought.

But it wasn't to last. The second application caused severe redness, worse than anything I'd previously experienced. The third, fourth and fifth days were much the same. It has started to subside now but is still no better than before I started using it. Maybe I've been applying too much, or applying it too frequently? I'm going to apply it to a small patch of my forehead for a few weeks before deciding whether to continue use on the rest of my face.

[Brady Barrows]

Hello there

I recently bought Mirvaso from 'pharmacy2u' in the UK. I've been using it for about a week now. About an hour after first use I noticed the redness had gone completely - in fact I looked slightly pale. Wonder drug, I thought.

But it wasn't to last. The second application caused severe redness, worse than anything I'd previously experienced. The third, fourth and fifth days were much the same. It has started to subside now but is still no better than before I started using it. Maybe I've been applying too much, or applying it too frequently? I'm going to apply it to a small patch of my forehead for a few weeks before deciding whether to continue use on the rest of my face.

Aldous,
Please keep us informed of your decision of whether you will continue using Mirvaso or not. Thanks for your initial report.

[Vovin]

https://twitter.com/DrMervPatterson/status/457437479529111552

Rebound/worsening of facial redness, one bordering on blue discolouration reported by two of my patients who tried Mirvaso Gel #Rosacea

[nat007]

https://twitter.com/DrMervPatterson/...37479529111552

Rebound/worsening of facial redness, one bordering on blue discolouration reported by two of my patients who tried Mirvaso Gel #Rosacea

That's what this dr Mervyn Patterson did to my face too, after the IPL treatment I had with him. He blamed it on assumed stress over the death of my sister earlier that year, conveniently. But nice of him to speak out against Mirvaso :/

For those interested in some French rosacea patients reviews, they can be found here: http://www.rosacea.fr/mirvaso-gelbrimonidine_3_1740.php
I speak some French and translated them here: http://scarletnat.blogspot.fr/2013/1...responses.html

g30 wrote on April 16th 2014: "Bonjour a tous! J'ai le mirvaso . Des mois et des mois que j'attends j'ai mis.beaucoup d'espoir.dans cette crème... résultats.... déception.... pourquoi? Parce que trop.efficace . Après l'application l'effet est immédiat 10 min pour.moi. et la le visage blanc mais blanc de chez blanc ça donne un effet "malade" en plus il.faut vraiment bien l'étaler car cela peut ressortir non uniforme.... bref il l'est impossible d'utiliser ça le.jour. la différence serait vraiment trop importante. On me demanderai si je me sent bien... je songe a l'utiliser le soir après le.sport par exemple pour faire derougir.le.visage et éviter les boutons du a la rosacé... mais je n'ai pas assez de recul ... cette le visage est blanc mais je me demande si quand l'effet se dissipe le sang n'abonde pas +"
Translation in English as good as I can:
"Hello everyone! I have some mirvaso. I have waited months and months. I have built up high hopes for this cream. Results.. disappointment .... why? Because it's too powerful. After application the effect is immediately visible, within 10 minutes, for me. And my face becomes white, but a shade of white that makes me look sick. It also does't spread in a uniform (evenly) manner. So, it is impossible to use daily for me. The change is too massive. People ask me if I am feeling well or not. I am thinking about using it in the evening, after sport for instance, to avoid getting a red face and to avoid the ...(to avoid looking like I have rosacea, I think. Couldn't translate this part). But I do not have enough to recline ... my face is white but I wonder if the effect wears off when the blood does not circulate anymore"

g30 then updated on April 22nd 2014 (translated in English again):
"WARNING MIRVASO IS DANGEROUS!! I have post you my first impressions the other day ... today is the catstrophe. I am forced to stay home, because it was impossible for me to go to work in this state ... my face is on fire! ! The redness is everywhere and I feel like I have a sunburn all over my face. I only used the mirvaso for 3 days ... and I have already seen the unwanted side effects! On the second day I felt my skin was clearer and improved ... then in the evening, diffuse redness appeared, followed by a huge sense of heat across my face ... (can;t properly translate this sentence but I think he/she means that it is calming down a bit again after some sleep) ., but for how long? The nexy day was the same situation ... I wake up and then as the day goes by without application of the product the redness appears again ... to which I begin again... "

Doremi wrote on April 25th 2014:
"Hello, I am new to the forum, but not to rosacea (I mainly have flushing of the nose). I have this since 6 years and I manage it with low doses of beta-blockers + roaccutane and Azelaic acid (the equivalent of Finacea). I have used Mirvaso for more than 15 days, and just like g30, when I use it pure, it equals a return to white skin for about 8 hours and then the rebound redness takes place + heat sensations on the spots and areas where I applied mirvaso (even those where I don't usually flush). However, like can be read on the forums from the United States, I do not have a rebound effect when I dilute it + + with a cream or gel (Azelaic acid for me). It must indeed apply a very tiny amount of mirvaso, so that it can mix with a gel or a cream. "

g30 then replied and UPDATED on April 26nd 2014:
"Thank you for your reply ... it's been one week and I am still very red, even though it is starting to fade. I have no desire to start experimenting again with a diluted cream. The more I think about it, the more I personaly am convinced that playing with your blood vessels will strongly weaken and damage them. I cross my fingers to return to the state my face was in before ... and if this by chance happens, I will not touch it again. Sessions of laser maintenance will be enough, I have not tested any creams until now, it was not worse thing every time ... the mirvaso has marked me and I doubt things will return to normal. In short ... "

clubberjack wrote on May 2nd 2014:
"Bonjour, J'ai eu exactement le même problème que g30.. j'ai utilisé mirvaso 3 fois! La première fois j'étais vraiment super content du résultat. . J'avais jamais eu un visage aussi pâle.. Par contre à la 3 eme application ça a été l'horreur, enorme flush dans la journée.. C'était il y a une semaine. . Depuis j'ai des flush beaucoup plus souvent et beaucoup plus prononcés c'est l'horreur. . J'ai l'impression d'avoir un énorme coup de soleil..tout le monde me le fait remarqué. . Ce produit est un vrai poison.. à ne jamais essayer !!!"
Translate in English:
"Hello, I had exactly the same problem as g30 .. I have used mirvaso 3 times! The first time I was really super happy with the results. . I have never had such a pale face .. However, by the 3rd application it turned into horror, and I developed a huge flush during the day .. That was a week ago.. Ever since I have flushed a lot, much more often and much more pronounced; it is horror. . I feel like I have a huge sunburn .. everyone makes comments about it. . This product is a true poison .. never ever try it!"

[Vovin]

Doremi wrote on April 25th 2014:
"Hello, I am new to the forum, but not to rosacea (I mainly have flushing of the nose). I have this since 6 years and I manage it with low doses of beta-blockers + roaccutane and Azelaic acid (the equivalent of Finacea). I have used Mirvaso for more than 15 days, and just like g30, when I use it pure, it equals a return to white skin for about 8 hours and then the rebound redness takes place + heat sensations on the spots and areas where I applied mirvaso (even those where I don't usually flush). However, like can be read on the forums from the United States, I do not have a rebound effect when I dilute it + + with a cream or gel (Azelaic acid for me). It must indeed apply a very tiny amount of mirvaso, so that it can mix with a gel or a cream. "

This is what I'll likely do if it ever comes to Canada. Dilute the Mirvaso with 75% moisturizer and see if any reduction in redness occurs. At this point I've given up on the notion of completely pale skin, I'll settle for just a slight reduction in redness.

[wiry]

This is what I'll likely do if it ever comes to Canada. Dilute the Mirvaso with 75% moisturizer and see if any reduction in redness occurs. At this point I've given up on the notion of completely pale skin, I'll settle for just a slight reduction in redness.

Been tried many times already (and I tried myself). All it will do is reduce the intensity of how it works and the intensity of your rebounds. But you will suffer rebounds still and damage your skin in the long term. There is no way to Mirvaso where that will not be the case.

[johnabetts]

I would like to make the point that it shouldn't be incumbent on the patient (user of this product) to get involved in making dilutions or other changes to a product before it is suitable or safe to use.

If the product is too strong in its action for most, or even just some, users then it ought to be available in different concentrations to suit.

[red devil]

I've been trying the smallest amount to the side of my cheek.I am under no illusions that i wont get rebound flushing but the effects have been interesting.
Where i applied it the skin stayed pale for a good day and a half.

[red devil]

In the bin goes the mirvaso.I was daft enough to try it,so only myself to blame.

[nat007]

In the bin goes the mirvaso.I was daft enough to try it,so only myself to blame.

Could you tell us what went wrong? The to be expected?

[red devil]

Could you tell us what went wrong? The to be expected?

The first time i tried it it worked wonders.My face went pale for at least 2 days with only one application.
The next time i tried it it took a little while to lower the redness but had no problems.Then i used it once more, but decided to leave it a few days to see if anything would happen.About 3 or 4 days after last application my face started flushing more than normal.My face seems to be flushing all the time forcing me to hold a fan to try and cool down,even have to have the fan on at night.I had started clonidine about a week before,so don't know if that has added to the problem.All in all not a good experience.